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Omega XL Review
Does It Really Work?

Isaac Robertson
Published by Isaac Robertson
Fact checked by Donald Christman, BHSc FACT CHECKED
Last updated: October 21, 2021

The Omega XL supplement is popular for two main reasons - the online raves and Larry King.

The product claims to benefit those who suffer from joint pain and inflammation, whether due to aging or exercise

As such, Omega XL is a favorite supplement among older folks, which probably explains Larry King’s strange, incongruous promotion of it…

Mr. King aside, tons of Omega XL reviews online are mostly positive.

But does Omega XL live up to the hype? Our team with our resident dietitian spent almost a month's worth of research - ingredients and clinical studies included - to see if this product does.

Let's get into the details of our research with this Omega XL review.

What is Omega XL?

A woman holding an Omega XL product

Omega XL is a dietary supplement that contains more than 30 different fatty acids. It contains a blend of omega-3 fatty acids, all of which are sourced from natural ingredients.

Instead of obtaining the essential fatty acids from fish or algae, which can give a fishy aftertaste like any other fish oil extract, this product sourced them from green-lipped mussels.

Many arthritis organizations have recommended natural ingredients (derived from the green-lipped mussels) to relieve joint pain, especially for older people who may be more sensitive to synthetic products than young people.

Omega XL is intended to be taken 1-2 times a day, depending on your weight. It is always advised to consult your doctor for a proper dosage recommendation, rather than relying solely on reviews or manufacturers' claims.


Celebrities who use this supplement:

Products Similar to Omega XL

Or, you can see our main review of the best omega-3 supplements for more omega 3 insights.

Omega XL Active Ingredients

Supplement Facts of OmegaXL

So what does Great Healthworks claim to actually be in this product?

  1. PCSO-524™ – According to a recent study, Perna Canaliculus Green-Lipped Mussel Extract or PCSO-524™, is 89% more effective for easing joint pain compared to regular fish-based supplements. This ingredient is unique to Omega XL, but current studies fail to support the effectiveness of green-lipped mussel extract.
  2. Omega-3 Fatty Acids – These fatty acids are known for helping relieve painful joints, and some studies suggest that they also act as a natural anti-inflammatory. However, the dose is relatively low compared to other omega-3 supplements.
  3. Vitamin E - Commonly found in olive oil, vitamin E has numerous health benefits, such as improving skin and nail health.
  4. Monounsaturated Olive Oil – Monounsaturated olive oil (i.e. extra virgin olive oil) is known as the healthiest fat on earth, and it’s easy to see why.

MUFAs (monounsaturated fatty acids) have been found to lower total cholesterol and low-density lipoprotein (LDL) cholesterol levels. In addition, some research shows that MUFAs may benefit insulin levels and blood sugar control, which can be helpful if you have or are at risk of type 2 diabetes.

- Katherine Zeratsky, Dietitian


Omega XL

Omega XL contains a blend of fatty acids and other natural ingredients that help support joint health, making it popular with older people who might otherwise use some regular fish oil extract.

Elders suffering from osteoarthritis typically lack vitamin E in their diet, so a supplement like Omega XL may be prescribed.

Most users report that it didn’t work to relieve their joint pain and inflammation due to arthritis even after months of consistent use.

With an all-natural formula, the manufacturer also claims that it may relieve muscle soreness due to exercise.

However, in my experience, I did not feel any significant relief in terms of muscle pain and soreness after workouts.


Omega XL comes in soft gel capsules, which is something most elders appreciate. My clients and I loved how it lacks the fishy aftertaste, unlike most omega-3 supplements.

  • Extracted from green-lipped mussels to avoid a fishy aftertaste
  • Toxin-free and fights free radicals
  • Improves joint health and can improve mobility and vitality
  • Small easy-to-swallow soft capsule
  • Quite expensive
  • Some customer reviews spoke about seeing no effects
  • Quality of ingredients such as the green-lipped mussel extract is not established

Side Effects

joint pain

There are side effects of taking too much omega-3 fatty acids (from any source), including high blood sugar, low blood pressure, and diarrhea.

After taking Omega XL, some users noticed gaining more weight after taking pills. Other side effects reported were headaches and abdominal pain. Others also mentioned that it did nothing to improve the mobility or health of their joints.

However, the effect on pain relief seems to be a common answer in a number of Omega XL reviews -- joint pains were reportedly reduced, albeit temporary.

Some users also noted that 6 capsules a day or 2 capsules thrice a day is a good starting point as you gradually increase the dose to 8 capsules to feel the desired results.

Furthermore, the steep price is a common pain point among users, and there’s no denying that the Omega XL supplement is on the expensive side when compared to other supplements out there.

Where Can You Buy Omega XL

You can buy a bottle of Omega XL (either the 60-capsule or 300-capsule) on But it is also available on the manufacturer's website.

Omega XL Cost

Each bottle has 60 capsules which is good for 15 days only based on the recommended daily dosage of 4 capsules. It costs around $50, depending on where you buy it, but you can also get 2 bottles for a discounted price of $94.99.

For active users of Omega XL, you can also buy the 300-capsule bottle at $219.99 to save more. But even with this discount, I still find it very expensive than other omega-3 supplements.

You can check this website for the most up-to-date price of Omega XL.

Shipping and Returns

You can order your bottles on and it offers worldwide shipping at a fee.

For customers located in the US and Canada ordering on the manufacturer's website, Omega XL offers a 60-day money-back guarantee for any reason you're unsatisfied. Simply return the product (whether used or unused) within 30 days from the refund request.


omega xl and muscle pain

Is Omega XL better than fish oil?

Omega XL may be more beneficial than fish oil for some users due to the the green-lipped mussel extract, PCSO-524™, which clinical studies have found to be an effective ingredient for treating joint pain.

Is Omega XL good for your heart?

Omega XL claims to be good for your heart health due to its omega-3 fatty acids. These fatty acids can help decrease triglycerides, lower blood pressure, and reduce the risk of stroke and heart failure.

However, it is worth noting that the body cannot absorb and make use of omega-3 without other omega fatty acids.

Does Omega XL help with arthritis?

Omega XL may help with rheumatoid arthritis and other joint problems due to its omega-3 fatty acids and PCSO-524™.

Is Omega XL good for back pain?

Omega XL may be good for back pain as it claims to reduce inflammation in your body.

However, if you’re looking to specifically target and reduce your back ache, you may want to look for other medicine.

Is Omega XL good for fibromyalgia?

Omega XL may be good for fibromyalgia as omega-3 fatty acids could help reduce symptoms. However, you should consult your physician for the best medication to take.

Omega XL website

Is Omega XL good for lowering cholesterol?

Omega XL may help lower cholesterol due to the omega-3 fatty acids. These fatty acids can effectively reduce body inflammation, decrease plaque growth in your arteries, and help thin your blood.

Is Omega XL good for diabetes?

Omega XL may be good for diabetes if taken as part of a recommended healthy diet. According to studies, omega-3 fatty acids, together with omega-7 and -9, can help prevent any health issues such as fatty liver. However, you should always consult your physician about the best medication and supplement to take.

Is Omega XL a fat thinner?

No, Omega XL is not a fat thinner. Some users share side effects of loose stools and diarrhea, which can lead some people to think that the product is a fat thinner. However, it is primarily intended for joint pain relief in older people.

Is Omega XL approved by the FDA?

No, this Omega XL product is not approved by the FDA.

Should You Buy Omega XL?

The bottom line is that Omega XL may work for older people with joint problems who need a pain reliever. The ingredients are similar to many omega-3 supplements, but the user reviews seem to be more mixed.

Since Omega XL contains omega-3 fatty acids sourced from green-lipped mussels, it doesn’t have a fishy aftertaste, something that a lot of users seem to like.

However, some people are quite hesitant with the product's effectiveness since the quality of vitamin E from the olive oil and green-lipped mussels is not yet established.

If you're on the lookout for a premium omega-3 supplement, I highly recommend OmegaWell from Live Conscious instead.

It has a strong dose of EPA and DHA (800 and 600 mg, respectively) -- one of the strongest and most potent in the market today.

It also doesn't contain any preservatives and the ingredients are 100% sustainably sourced.

Our #1 Recommended

OmegaWell by Live Conscious

OmegaWell by Live Conscious
Ingredient quality
Overall Score
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  • The added lemon flavor reduces the chance of fishy burps (from the fish oil)
  • One of the strongest doses of EPA and DHA
  • Available with good bulk-order discounts
  • The small soft gels seem to be easy to swallow
  • A bit pricey


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8 thoughts on “Omega XL Review
Does It Really Work?

  1. I have arthritis in my back, legs, and headaches from migraines, and I would say that it definitely targets the inflammation.

  2. It works GREAT FOR ME, MY WIFE AND MOTHER WHO IS 76 years old , I’m aware that some people have symptoms that this won’t help and ARE THE FIRST TO COMPLAIN but after MY OWN PROVEN TEST STUDY against store bought products , my wife started using it AND AGAIN with GREAT RESULTS and now won’t go without it. We were introduced to Omega XL by my old mother who gave it to us for free to try. Now she gets it free from our subscription.,,

  3. Thank you for all the posts on this product. Not spending any money for this omega xl fraud

  4. Good day! I simply would like to offer you a big thumbs up for your great information you’ve got right here on this post.
    I’ll be coming back to your website for more soon.

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