Creatine vs Creapure - Which Form is Better?

Dr. Harshi Dhingra, MBBS, MD
Published by Dr. Harshi Dhingra, MBBS, MD | Medical Doctor
Last updated: March 26, 2024
FACT CHECKED by Dr. Kristy Dayanan, BS, MD
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Creapure and traditional creatine supplements may significantly impact your training outcomes. These supplements play a crucial role in many fitness routines by aiding in muscle mass, strength, and endurance.

So, how do you determine which one is best suited for your fitness regimen?

As a physician, I am sharing my knowledge about their differences, effects, and what makes creapure "purer."

Before you try and prepare your own creatine doses, read on and find out how these supplements can help you achieve your desired fitness goals.

Quick Summary

  • Creatine and creapure are two different products that optimize athletic performance and muscle growth.
  • Creapure offers advantages such as increased muscle mass, improved power, and enhanced muscle endurance.
  • Creapure, with its 99.99% purity and additional purifying processes, is considered a superior form of creatine compared to regular creatine.
  • Although both Creapure and regular creatine offer benefits, I believe Creapure's purity justifies its premium price, delivering tangible results in muscle growth, power, and strength for serious fitness enthusiasts.

Creapure vs Creatine

man looking through his supplements

The advantages of taking Creapure over traditional creatine are more than apparent.

Still, Creapure is way more expensive than regular creatine because of the additional purifying processes it goes through. So, you should seriously consider if it's worth the extra price.

Many professional athletes, myself included, believe it's worth it and are willing to pay extra for the difference that 0.09% makes.

Regular creatine typically contains impurities such as Dihydrotriazine (DHT). They're usually present in creatine when inferior raw materials are produced.

Dihydrotriazine (DHT) doesn't occur naturally in the human body.

Its pharmaceutical and toxicological properties are still unknown, but researchers discovered that it's structurally similar to compounds shown to have carcinogenic properties.

This is another reason many creatine users decide to use Creapure.

What is Creapure?

Creapure is a brand name for pure creatine monohydrate made by the German company AlzChem Trostberg GmbH. It's essentially a more refined form of creatine.

After using it, I felt it was a purer form of creatine.

However, to better understand Creapure, I need to explain some basics to you.

What is Creatine?

golden spoon filled with powder and a white pill

Creatine is an essential amino acid produced by our bodies naturally. It has a vital role in transporting and storing energy in our muscle cells.

Like other substances, it's processed by our liver and kidneys.

Research published in the National Library of Medicine has discovered that creatine is the most effective supplement for high-intensity training, explosive activities, weight lifting, sprinting, football, baseball, and other sports that require short bursts of energy [1].

The adult human body has 80–130 grams of creatine, which is just half of what we need, and spends between two and four grams per day with regular activity.

Since high-intensity training requires higher creatine intake, we need to consume it in the form of a dietary supplement.

How Creatine Works?

male and female body shot of their lean bodies

High-quality creatine supplementation works by giving you more energy to sustain more reps. Every time your muscle cells contract during a workout, they lose phosphate and transform into ADP (Adeno-diphosphate).

Since your body can't use ADP to create the energy, it dips into your energy storage — phosphate creatine reservoir (PCR), during a workout, takes a phosphate and transforms the ADP into ATP (adenosine triphosphate).

ATP is the energy currency stored in your muscle cells, which is also the only acceptable energy currency for the body.

How to Supplement with Creatine?

woman taking a pill to her mouth while holding a glass of water

You can supplement with different types of creatine available on the market, and some are even marketed with bold claims not supported by research. Creatine monohydrate is the oldest, most studied, and used form of Creapure creatine. Hundreds of studies support its effectiveness and safety.

Some of the Benefits of Creatine Use Include:

  • Increasing muscle creatine stores by 10–40%, depending on your and your body's current creatine levels. If your levels are low, you may see even better results. You can achieve this by loading.
  • The loading phase is the quickest way to maximize the amount of creatine. You load by taking a high dose for a couple of days and then a lower dose for another few days.
  • Typically, this would mean taking 20–25 grams of creatine per day, in 5-gram doses, for 5–7 days. You would then follow this with a maintenance dose of 3–5 grams per day.
  • One study even suggests that creatine absorption can be improved with protein or carbohydrates [2], so you may want to think about taking creatine with your meal to achieve better results.

What Makes Creapure “Purer”?

white pills scattered on the table and a powder in a bowl

The technical process of making Creapure creatine is what makes it purer compared to other types of creatine. AlzChem uses specialized facilities where they purify regular creatine monohydrates from dicyandiamide (DCD), Dihydrotriazine (DHT), Thiourea, and Creatinine (CTN).

While most creatine supplementation on the market have 99.9% creatine and a couple of other ingredients, Creapure contains 99.99% pure creatine monohydrate.

Even though it’s just a 0.09% difference, many athletes prefer Creapure creatine since even that amount of creatine can make a huge difference in their performance.

Creapure vs Other Forms of Creatine

man raising up two different containers

Creatine Ethyl Ester (CEE) is very popular because, unlike other creatine supplements, it's easy on the stomach because the body processes creatine better.

It doesn't cause the most common side effects, but researchers have discovered that it's neither better nor worse than regular monohydrate.

“Creatine ethyl ester did not show any additional benefit to increase muscle strength or performance than creatine monohydrate or maltodextose placebo. Additionally, total body mass, fat mass, fat-free mass, and thigh muscle mass were not significantly enhanced with creatine ethyl ester supplementation compared to placebo or creatine monohydrate groups.”

- Mike Spillane, Ryan Schoch, Matt Cooke, Travis Harvey, Mike Greenwood, Richard Kreider & Darryn S Willoughby

The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels.

CEE is also popular because it can be taken in smaller doses than regular monohydrate, delivering the same results.

Creatine Hydrochloride — HCL

HCL is known for its superior solubility in water compared. A study by Brandon T Gufford, Kamaraj Sriraghavan, Nicholas J Miller, Donald W Miller, Xiaochen Gu, Jonathan L Vennerstrom, and Dennis H Robinson discovered that HCL is 38 times more soluble compared to regular monohydrate [3].

Due to this, it can be used in lower doses (1.5 grams per day compared to the standard creatine dose of 5–10 grams), hence avoiding common side effects, such as an upset stomach.

Buffered Creatine

Buffered creatine, or kre-alkalyn, is a blend of regular monohydrate creatine and alkaline powder. It was made specifically to improve creatine’s stability in the stomach. It increases your power and reduces side effects such as bloating.

Liquid Creatine

Even though popular, liquid creatine is less effective than other forms because creatine breaks down if sitting in liquid for several days.

Creatine Magnesium Chelate

Creatine magnesium chelate is essentially a monohydrate with an attached magnesium molecule. It's as effective as other forms, but not better.

What all these types of creatine have in common is that they're mass-produced. Hence, you can't know for sure how pure they are unless you thoroughly study each ingredient.

On the other hand, Creapure is 99.99% pure, which is essential for muscle growth and performance increase.

3 Reasons to Switch to Creapure

white man in a white shirt showing off his biceps

If you still can't decide on whether you should switch to Creapure, here's a shortlist of key reasons that will persuade you:

1. Purity

As I mentioned, Creapure contains 99.99% pure creatine, which is essential for every serious athlete. It guarantees quality, power, and more muscle.

2. More Muscle

Since it’s purer than other normal creatine supplementation, Creapure has a higher concentration of phosphocreatine that replenishes your ATP reserve sooner.

This gives you more power and enables you to last longer in the gym. This means that you'll increase your number of reps which will then show in your muscle growth.

Creapure benefits will show in a larger muscle mass. Since creatine pulls water in your muscle cells to trigger protein synthesis, your muscles will swell mainly from water when you start taking the supplement.

However, later it will be actual muscles — a result of your hard and extended workout.

3. More Power

During exertion, creatine users notice a smaller decrease in muscle pH. As you know, creatine supplements are incredibly beneficial in sports that require speed and explosiveness, such as sprinting, long jump, or swimming.

Bodybuilders who engage in intensive strength training improve performance in the areas of maximum strength and endurance by using a creatine supplement.

When Should I Take Creapure?

A fit woman holding an empty pill bottle

You should take Creapure either less than one hour before or immediately post-workout. Using it after the workout is more beneficial since high-intensity training stimulates blood circulation and supplies cells with creatine more quickly.

Nevertheless, you can take Creapure when most convenient to you.

Taking Creapure During Exercise-Free Periods

For the best effects and most benefits, you should take creapure continuously. Therefore, it is recommended for one to have a daily dose of 3–5 g of creapure.

Effects of Creatine on Athletic Performance

Creatine, and particularly Creapure, have three main impacts on athletic performance across different sports:

  1. Performance in Endurance Sports: While creatine is known for its impact on high-intensity sports, it can also benefit endurance athletes by improving energy efficiency and reducing fatigue.
  2. Benefits of Team Sports: In sports like soccer or basketball, where explosiveness and endurance combine, Creapure can offer advantages in recovery between short, explosive efforts.
  3. Impact on Water Sports: Swimmers and other aquatic athletes can benefit from creatine by enhancing power in short sprints and endurance over longer distances.


What Makes Creapure Better?

What makes Creapure better is its 99.99% purity, ensuring optimal absorption and fewer impurities than regular creatine.

Can I Just Take Creatine Daily?

Yes, you can take creatine daily because it supports muscle growth and recovery, but always monitor the dosage and stay hydrated.


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About The Author

Dr. Harshi Dhingra, MBBS, MD is a published peer-reviewed author and renowned physician from India with over a decade of experience. With her MBBS from Bharati Vidyapeeth and an MD from Rajiv Gandhi University, she actively ensures the accuracy of online dietary supplement and medical information by reviewing and fact-checking health publications.
Learn more about our editorial policy
Dr. Kristy June Dayanan, BS, MD is an author with a BS degree from University of the Philippines and an MD from University of Perpetual Help System. Her ability to simplify medical science complexities and dietary supplement jargon for the average reader makes her a valued medical fact checker and reviewer.
Learn more about our editorial policy

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