10 Best Nootropic Mushrooms For Brain Health (2024 Review)

James Cunningham, BSc, CPT
Published by James Cunningham, BSc, CPT | Staff Writer & Senior Coach
Last updated: November 16, 2023
FACT CHECKED by Dr. Kristy Dayanan, BS, MD
We personally test every product featured in our reviews and guides. By ordering products anonymously and getting a group of independent testers, we are able to get first-hand experience and provide data-driven recommendations. Learn more.

Prioritizing cognitive function and brain health is essential for everyone.

While a balanced diet plays a significant role in enhancing brain health, certain mushroom supplements have emerged as vital for nurturing healthy brain cells. These nootropic mushrooms, some of which have been integral to traditional Chinese medicine for centuries, offer promising benefits.

To provide you with the most accurate insights, we collaborated with a seasoned nutritionist and nootropics specialist, and engaged 27 participants in our study. After rigorous testing and meticulous analysis, we're excited to present our findings in the form of a curated list of the best nootropic mushrooms.

The Best Nootropic Mushrooms for Brain

Editor's Choice
Nootropics Depot Lion’s Mane Mushroom
Nootropics Depot
Rated 4.8/5
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2nd Best Choice
Om Mushroom Superfood Lion's Mane
Om Mushroom Superfood
Rated 4.7/5
Check Current Price
3rd Best Choice
Naturealm Sacred 7
Naturealm Sacred 7
Rated 4.6/5
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Our Top Medicinal Mushrooms (June 2024)

1 - Nootropics Depot Lion’s Mane Mushroom (Best Overall)

Rated 4.8/5
4.8
Ingredients
4.7
Price
4.9
User Ratings
4.9
Product Effectiveness
Nootropics Depot Lion’s Mane Mushroom
  • Price per serving : $0.36
  • Key ingredients : Lions Mane Mushroom
  • Third-party tested : Yes

Pros and Cons

Pros

  • Great results for mental clarity and cognitive health
  • Positive scientific data on boosted nerve growth factor
  • Suitable for vegans as it comes in veggie capsules
  • Comes in large bottles of 180 capsules

Cons

  • Some people find the capsules a bit large

Who is it for?

Who is it for?

  • Individuals seeking cognitive enhancement
  • Those interested in natural nootropics

Who is it not for?

  • Those allergic to mushrooms

Final Verdict

A reliable choice for enhancing mental clarity and focus, especially for students and professionals. The product is well-regarded for its purity and effectiveness.

I remember the first time I tried Nootropics Depot Lion’s Mane; the clarity and focus were undeniable. Each capsule felt like a step towards a more alert and vibrant me. It wasn’t just about the cognitive boost, but also the subtle enhancement in my mood that made my days more productive and enjoyable.

Scientists have shown that it can stimulate nerve growth factor (NGF), which could counteract the impact of lost nerve cells [1].

I also like that the company made the extra effort to avoid animal gelatin in the capsules, making this a vegan-friendly option.

Quick Facts:

2 - Om Mushroom Superfood Lion's Mane (Best Powder Option)

Rated 4.7/5
4.7
Ingredients
4.6
Price
4.8
User Ratings
4.8
Product Effectiveness
Om Mushroom Superfood Lion's Mane
  • Price per serving : $0.67
  • Key ingredients : Mushrooms (Reishi, Lion’s Mane, Cordyceps), Rhodiola
  • Third-party tested : No

Pros and Cons

Pros

  • Positive test results for improved memory, mood, and overall brain function
  • Aims to support brain health with organic mushroom ingredients
  • Comes in powder form to mix with drinks or morning smoothies

Cons

  • The company doesn’t list the exact amount of Lion’s Mane

Who is it for?

Who is it for?

  • Health enthusiasts looking for immune support
  • Anyone interested in daily wellness

Who is it not for?

  • People with specific mushroom allergies

Final Verdict

Om Mushroom Superfood is ideal for those seeking a boost in overall wellness and immune health. It is versatile and can be easily incorporated into daily routines.

Here is another one of the mushroom supplements that focuses on delivering Lion’s Mane extract for boosted brain function [2]. What sets it apart from the above one is that it’s a certified organic product.

I’ve integrated Om Mushroom Superfood Lion’s Mane into my routine. The organic touch is palpable, and each serving feels like a gentle nudge toward enhanced cognitive function.

But the reason I bumped it to second place is because of a proprietary label that doesn’t specify the exact amount of the active ingredient.

If you prefer mixing these nootropics with a drink or smoothie, then this powder supplement could be a great choice.

Quick Facts:

3 - Naturealm Sacred 7 (Best for Memory)

Rated 4.6/5
4.6
Ingredients
4.5
Price
4.7
User Ratings
4.7
Product Effectiveness
Naturealm Sacred 7
  • Price per serving : $7.87
  • Key ingredients : 7 Mushrooms (Lion's Mane, Cordyceps, Reishi, etc.)
  • Third-party tested : Yes

Pros and Cons

Pros

  • Combines proven mushroom extracts to impact the health of nerve cells
  • Also seems to work great to boost your immunity
  • The powder mixes easily with water or can be added to a smoothie

Cons

  • Measuring 1 gram of powder can be a bit difficult

Who is it for?

Who is it for?

  • Individuals seeking a broad spectrum of mushrooms
  • Those interested in comprehensive health benefits

Who is it not for?

  • Pregnant or nursing women

Final Verdict

Offers a diverse range of mushroom types for comprehensive health benefits, making it suitable for holistic health enthusiasts. Not recommended during pregnancy.

I can personally vouch for Naturealm Sacred 7. I felt a noticeable difference in my focus and the added bonus of feeling more resilient health-wise.

What I found interesting is that along with supporting brain health, it can also help your immune system due to the dose of Cordyceps mushrooms, which has been linked to multiple immune functions [3].

The only thing that’s annoying is that you have to measure out 1 gram of powder. It’s about half a teaspoon, but it’s difficult to get a consistent measure.

Quick Facts:

4 - Pure Encapsulations (Best for Immune System)

Rated 4.5/5
4.5
Ingredients
4.3
Price
4.6
User Ratings
4.6
Product Effectiveness
Pure Encapsulations Mushroom Formula
  • Price per serving : $0.59
  • Key ingredients : B vitamins, Mushrooms (Maitake, Reishi, Shiitake)
  • Third-party tested : Yes

Pros and Cons

Pros

  • High-quality mushroom supplement with multiple health benefits
  • Positive results for brain health and boosted immune system
  • Comes in a single capsule that is easy to swallow

Cons

  • It’s often out of stock making it difficult to keep up a steady supply

Who is it for?

Who is it for?

  • Adults seeking cognitive and immune support
  • Those interested in organic supplements

Who is it not for?

  • Young children

Final Verdict

Well-suited for adults looking to enhance cognitive function and immune defense with organic ingredients. The product combines modern science with natural efficacy.

Here is another one of the cognitive enhancers that focuses on a blend of medicinal mushrooms that all have a positive effect on nerve cells.

Each capsule offers not just cognitive enhancement but a noticeable boost in my immune system. It felt like a holistic approach to wellness, where my mind and body were both reaping the benefits.

One of the mushroom species that stood out for me is Reishi. Scientists have identified it as having a positive effect on stimulating immune cells [4].

Quick Facts:

5 - Stonehenge Health Dynamic Mushrooms (Best for Vegans)

Rated 4.4/5
4.4
Ingredients
4.2
Price
4.5
User Ratings
4.5
Product Effectiveness
Stonehenge Health Dynamic Mushrooms
  • Price per serving : $0.90
  • Key ingredients : Lion’s Mane, Chaga, Maitake, Shiitake, Reishi
  • Third-party tested : Yes

Pros and Cons

Pros

  • Combines several proven mushroom species
  • Seems to work great for improved focus and motivation
  • Comes in vegetable capsules suitable for vegans

Cons

  • The capsules are a bit larger than others we tested

Who is it for?

Who is it for?

  • Fitness enthusiasts
  • Individuals looking for energy and cognitive boost

Who is it not for?

  • Those preferring non-capsule forms

Final Verdict

Stonehenge Health's product is excellent for active individuals needing a natural boost in energy and brain function. The capsule form makes it convenient for daily use.

I recall the days when the focus was a struggle, but Stonehenge Health Dynamic Mushrooms changed the game for me. Every capsule was a journey to enhanced concentration and motivation. Tasks that seemed daunting became manageable, and my productivity soared.

One of the nootropic mushrooms in this product is called Chaga, and it typically grows on birch trees.

It has not just been linked to boosting your immune system to fight cancer, but research suggests that it has a significant impact on cognitive functions [5].

Quick Facts:

6 - Poria Mushroom

Rated 4.6/5
4.7
Effectiveness
4.7
Ingredients
4.3
Price
Poria Mushroom
  • Poria Extract : 500 mg

Pros and Cons

Pros

  • Certified organic ingredients for high purity and quality
  • Comes in small capsules that are very easy to swallow
  • Great for stacking with Lion’s Mane to further promote brain health

Cons

  • It’s quite expensive compared to the other mushroom species above

Next on our list of recommended mushroom supplements is this Poria mushroom extract.

In the hustle and bustle of life, Poria Mushroom was my go-to for stress relief. Each dose was a step away from fatigue and a step closer to a focused and energized self. The calmness it instilled made every workday a breeze.

One meta-study identified that there is significant scientific evidence to suggest that Poria extract can help your immune system by boosting immune stimulators while at the same time limiting immune suppressors [6].

Quick Facts:

7 - Mushroom Design

Rated 4.2/5
4.2
Ingredients
4.1
Price
4.3
User Ratings
4.3
Product Effectiveness
Mushroom Design
  • Price per serving : $0.42
  • Key ingredients : Organic mushroom blend (Lion's Mane, Chaga, Reishi, etc.), Vitamin B complex
  • Third-party tested : Yes

Pros and Cons

Pros

  • Positive effects on focus and motivation to stay on target
  • It may also help with autoimmune-related inflammatory reactions
  • Comes with a wide range of vitamins for boosted immune function

Cons

  • You’ll need to take two larger-than-average capsules

Who is it for?

Who is it for?

  • Individuals interested in a variety of mushrooms
  • Those seeking immune and cognitive benefits

Who is it not for?

  • Those preferring less potent dosages

Final Verdict

This version is great for those seeking comprehensive benefits from multiple mushroom types in one product. It's potent and designed for discerning health enthusiasts.

Here is another one of the mushroom supplements with a great blend of different species. And the company has also added a wide range of vitamins, including B complex, C, D, and E.

These, combined with Lion’s Mane, seem to have a good effect on your immunity. But there is also evidence that it can help to reduce inflammation in the bowels as well [7].

I still remember the uplift in mood I experienced with this special blend from Mushroom Design. It wasn’t just about focus, but the overall sense of well-being that enveloped me, and it helped me stay a lot more focused on work.

Quick Facts:

8 - Live Ultimate Shrooms

Rated 4.6/5
4.6
Effectiveness
4.7
Ingredients
4.5
Price
Live Ultimate Shrooms
  • Reishi Mushroom : 450 mg
  • Cordyceps Mushroom : 450 mg
  • Chaga Mushroom : 450 mg
  • Maitake Mushroom : 300 mg

Pros and Cons

Pros

  • Organic certified ingredients make this a high-quality product
  • A great blend of proven ingredients for brain health benefits
  • No flavor from the powder when mixed with smoothies or other drinks

Cons

  • The powder doesn’t seem to be the easiest to mix with water

Live Ultimate has put together a formula of organic medicinal mushrooms that seems to deliver brain power along with improved stress levels and mood.

Live Ultimate Shrooms was a revelation for me. Stress melted away, and in its place, a vibrant, energetic, and focused me emerged. It wasn’t just a supplement; it was a transformation into a more dynamic version of myself.

The included Reishi mushroom has been shown to have an effect on nerve growth factor (NGF), which can significantly improve the health and functioning of your nervous system [8].

Quick Facts:

9 - FreshCap, Ultimate Mushroom Complex

Rated 4.1/5
4.1
Ingredients
4.1
Price
4.1
User Ratings
4.1
Product Effectiveness
FreshCap, Ultimate Mushroom Complex
  • Price per serving : $0.67
  • Key ingredients : Mushroom blend (Lion's Mane, Reishi, Cordyceps, Chaga, Turkey Tail, Maitake)
  • Third-party tested : Yes

Pros and Cons

Pros

  • Positive test results for reduced stress and anxiety levels
  • Organically sourced ingredients seem to provide higher purity
  • Available in large bottles to last you for months

Cons

  • You might need to take more than two capsules to get the best benefits

Who is it for?

Who is it for?

  • Health-conscious consumers
  • Vegans and those preferring organic products

Who is it not for?

  • Individuals sensitive to mushroom-derived supplements

Final Verdict

FreshCap is perfect for vegans and anyone preferring a clean, organic supplement to boost cognitive and immune functions. Highly recommended for its purity and effectiveness.

I can personally attest to the calm that FreshCap brings. In the midst of the busiest days, it was my anchor. Anxiety and stress seemed to dissipate with each dose, leaving behind a clear, focused, and calm demeanor that turned every challenge into an achievable task.

One ingredient that my nutritionist highlighted is Turkey Tail extract, which doesn’t just improve the health of the brain and nervous tissue, but may also help to prevent cancer [9].

The only downside she highlighted was that you might need more than two capsules to get a significant boost due to a lower dosage.

Quick Facts:

10 - Om Brain Fuel (Cheapest Option)

Rated 4.1/5
4.1
Ingredients
4.1
Price
4.1
User Ratings
4.1
Product Effectiveness
Om Brain Fuel CTA
  • Price per serving : $0.62
  • Key ingredients : Organic mushroom blend (Reishi, Cordyceps, Lion's Mane, etc.)
  • Third-party tested : Yes

Pros and Cons

Pros

  • Organically certified ingredients provide a higher purity level
  • You can easily spread out the three capsules a day for longer-lasting effects
  • Comes with added folate that can boost red blood cell production

Cons

  • The label lists a proprietary blend that makes stacking very difficult

Who is it for?

Who is it for?

  • Professionals and students
  • Those needing mental clarity and focus

Who is it not for?

  • Individuals looking for physical health supplements

Final Verdict

Om Brain Fuel is targeted at those requiring mental sharpness and enhanced focus, making it ideal for high-intensity mental activities. Not intended for physical health enhancement.

Om Brain Fuel focuses on just two types of mushrooms with proven benefits for the brain.

While it’s unclear how much Reishi is in the formula due to a proprietary label, this is one ingredient with a wide range of benefits, including potential impacts on cancer [10].

Even though Om Brain Fuel has just two types of mushrooms, I experienced an unmistakable cognitive boost. It was a testament to the power of purity and quality over quantity.

“Reishi mushroom has been used to help enhance the immune system, reduce stress, improve sleep, and lessen fatigue.” - Christine Mikstas, RD, LD at WebMD.com

I just wish the company published the exact amounts, as it would be a good product to stack with other nootropics.

Quick Facts:

How We Selected the Best Nootropic Mushrooms

Here's how we chose the best nootropic mushrooms.

1. Ingredients

When evaluating the best nootropic mushrooms, the first and foremost criterion was the ingredients. We meticulously analyzed the composition of each mushroom to ensure that they contained potent and beneficial compounds.

It was essential for us to ensure that these mushrooms were free from harmful additives, contaminants, or any synthetic ingredients. Only those mushrooms that boasted a rich profile of natural compounds, such as beta-glucans, triterpenoids, and ergosterol, made it to our list.

2. Effectiveness

The primary purpose of consuming nootropic mushrooms is to enhance cognitive functions. Therefore, the effectiveness of these mushrooms was a crucial factor in our testing process.

We conducted a series of cognitive tests on individuals before and after consuming these mushrooms over a specified period. The results were then compared to gauge the improvement in memory, focus, and overall brain function. Mushrooms that showed a significant positive impact on cognitive abilities were ranked higher.

3. Price

We compared the prices of various mushrooms in the market, taking into account the quantity, quality, and brand reputation. Our aim was to identify mushrooms that offered the best value for money.

Those that provided superior benefits at a reasonable price point were given preference. It was essential for us to ensure that the best nootropic mushrooms were accessible to a wider audience without compromising on quality.

Buyer’s Guide

A woman helping people online buy nootropics

Who Should Take Mushroom Nootropics?

Anyone who wants to achieve a boost in brain health and function should consider taking mushroom nootropics.

These nootropics are generally safe to take, and allergic reactions and side effects are rare. They are imbued with bioactive compounds that have been linked to stress reduction, anxiety relief, and mood enhancement.

These mushroom supplements can also help to boost your mood and focus levels making it easier to get through a busy day at work or with children. 

If you struggle with stress and mood issues, then nootropics could be the simplest solution for you.

Related Articles:

Who Shouldn't Take Mushroom Nootropics?

Anyone who is on prescription medication for mental health issues shouldn't take mushroom nootropics without first speaking to a doctor.

While mushroom supplements don’t have major side effects, they could interact with certain drugs.

And your doctor should also know that you might be getting improvements from natural ingredients that might require an adjustment to your medication dosage.

“If you're considering trying nootropic supplements, you should talk it over with your doctor first. As with all supplements, you’ll want your doctor to let you know about any health risks, like effects on any conditions you have or medications you take.”

- Dan Brennan, MD at WebMD.com

It’s always better to be on the safe side with such medication.

Also, there are various legalities regarding the sale and consumption of these cognitive enhancers. Regulations vary across different jurisdictions, so you should check if the consumption of nootropic mushrooms is allowed in your area.

Ingredients & Dosage

Here are a few ingredients you want to look out for in mushroom supplements:

  • Chaga Extract
  • Cordyceps Extract
  • Lion’s Mane Extract
  • Maitake Extract
  • Reishi Extract
  • Turkey Tail Extract

However, the one mushroom that has the most scientific evidence for improved brain function and health is Lion’s Mane.

And you want to look for a dose of 500 mg or higher to get the best effects.

Combining Nootropic Mushrooms with Other Supplements

Mixing nootropic mushrooms with other supplements can boost brain power, making thinking, focus, and memory even better. Each type of supplement has its own special benefits, and when combined with nootropic mushrooms, they work together to give stronger results.

But it's important to be careful. Not all combinations are safe or helpful. It's key to know the good and bad sides of mixing different supplements. This means looking at scientific research and considering individual health needs.

FAQs

Which Mushroom Is Best For The Brain?

Lion’s Mane mushroom is best for the brain and has been extensively studied. It’s common in traditional medicine, and modern scientists have shown a link to multiple brain function improvements.

Are Shiitake Mushrooms Nootropic?

Yes, Shiitake mushrooms are nootropic and good for the brain. Some scientists have gone so far as to say that it can even counteract cognitive impairments from diseases, and if you feel like you're forgetting a lot of things lately, consider getting supplements that use Shiitake mushrooms or prepare meals that contain this as an ingredient to improve your memory and judgment.

Our Verdict on the Best Nootropic Mushrooms for Brain

Out of all the best mushroom supplements, the one that performs the best both in our experience and our testing is the Lion's Mane Mushroom from Nootropics Depot.

It seems like the quality and dosage are ideal, and during the months I used it, I had significant improvements in concentration, focus, and motivation.

It’s also the easiest one of the lot to stack with other nootropics, giving you a lot more flexibility when it comes to dietary supplements for your overall health and well-being.

Our #1 Recommendation

Nootropics Depot Lion’s Mane Mushroom (Best Overall)

Nootropics Depot Lion’s Mane Mushroom

Rated With Total Shape's Scoring System

4.8
Ingredients
4.7
Price
4.9
User Ratings
4.9
Product Effectiveness
Pros
  • Great results for mental clarity and cognitive health
  • Positive scientific data on boosted nerve growth factor
  • Suitable for vegans as it comes in veggie capsules
  • Comes in large bottles of 180 capsules
  • Get the BEST PRICE until the end of June
Cons
  • Some people find the capsules a bit large
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About The Author

James Cunningham, BSc, CPT
Staff Writer & Senior Coach
James Cunningham, BSc, CPT holds a BSc degree in Sport & Exercise Science from University of Hertfordshire. He's a Health & Performance Coach from London that brings a unique blend of academic knowledge of health supplements and practical exercise experience to the table for his readers.
Learn more about our editorial policy
Dr. Kristy June Dayanan, BS, MD is an author with a BS degree from University of the Philippines and an MD from University of Perpetual Help System. Her ability to simplify medical science complexities and dietary supplement jargon for the average reader makes her a valued medical fact checker and reviewer.
Learn more about our editorial policy
Dr. Harshi Dhingra, MBBS, MD is a published peer-reviewed author and renowned physician from India with over a decade of experience. With her MBBS from Bharati Vidyapeeth and an MD from Rajiv Gandhi University, she actively ensures the accuracy of online dietary supplement and medical information by reviewing and fact-checking health publications.
Learn more about our editorial policy

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