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10 Best Nootropic Mushrooms For Brain Health (2023 Review)

Tyler Sellers
Published by Tyler Sellers
Fact checked by Donald Christman, BHSc FACT CHECKED
Methodology
We personally test every product featured in our reviews and guides. By ordering products anonymously and getting a group of independent testers, we are able to get first-hand experience and provide data-driven recommendations. Learn more.

Cognitive function and brain health should be a high priority for everyone.

And while diet can provide great improvements, there are some dietary mushroom supplements that are proving to be critical for healthy brain cells.

Such nootropic mushrooms have been around for a while, and some ingredients have been common in traditional Chinese medicine for centuries.

So, we decided to team up with a nutritionist and nootropics expert, as well as 27 clients, to research and test the most popular supplements.

After weeks of control tests and careful analysis, we now have a list to share with you.

Editor's Choice
CTA of Nootropics Depot
Nootropics Depot
Effectiveness
4.9
Ingredients
4.9
Price
5.0
Overall Score 4.9
4.9
Click For Best Price
#2nd Best Choice
CTA of Om Mushroom Superfood
Om Mushroom Superfood
Effectiveness
4.8
Ingredients
4.8
Price
4.9
Overall Score 4.8
4.8
Check Current Price
#3rd Best Choice
CTA of Naturealm Sacred 7
Naturealm Sacred 7
Effectiveness
4.7
Ingredients
4.8
Price
4.7
Overall Score 4.7
4.7
Check Current Price

Our Top Medicinal Mushrooms (January 2023)

1 - Nootropics Depot Lion’s Mane Mushroom (Editor's Choice)

CTA of Nootropics Depot
Effectiveness
4.9
Ingredients
4.9
Price
5.0
Overall Score 4.9
4.9

This is one of the Lion's Mane Mushroom supplements that gave our testing team the best possible results.

The most interesting thing about this mushroom is that scientists have shown that it can stimulate nerve growth factor (NGF), which could counteract the impact of lost nerve cells [1].

And many studies that looked into this effect used a similar dose to the 500 mg contained in this Nootropics Depot product.

We also like that the company made the extra effort to avoid animal gelatin in the capsules making this a vegan-friendly option.

The other thing that our testing team revealed after a few weeks is that it also seems to boost your immune system.

Quick Facts:

  • Lion’s Mane Extract : 500 mg
Pros
  • Great results for mental clarity and cognitive health
  • Positive scientific data on boosted nerve growth factor
  • Suitable for vegans as it comes in veggie capsules
  • Comes in large bottles of 180 capsules
Cons
  • Some people find the capsules a bit large

2 - Om Mushroom Superfood Lion's Mane

CTA of Om Mushroom Superfood
Effectiveness
4.8
Ingredients
4.8
Price
4.9
Overall Score 4.8
4.8

Here is another one of the mushroom supplements that focuses on delivering Lion’s Mane extract for boosted brain function [2]. What sets it apart from the above one is that it’s a certified organic product.

But the reason we bumped it to second place is because of a proprietary label that doesn’t specify the exact amount of the active ingredient.

If you prefer mixing these nootropics with a drink or smoothie, then this powder supplement could be a great choice.

Quick Facts:

  • Lion’s Mane Extract : n/a
Pros
  • Positive test results for improved memory, mood, and overall brain function
  • Aims to support brain health with organic mushroom ingredients
  • Comes in powder form to mix with drinks or morning smoothies
Cons
  • The company doesn’t list the exact amount of Lion’s Mane

3 - Naturealm Sacred 7

CTA of Naturealm Sacred 7
Effectiveness
4.7
Ingredients
4.8
Price
4.7
Overall Score 4.7
4.7

Naturealm has created a supplement of medicinal mushrooms that all seem to have enough scientific evidence for improving the health of nerve cells.

What we found interesting is that along with supporting brain health, it can also help your immune system due to the dose of Cordyceps mushrooms, which has been linked to multiple immune functions [3].

The only thing that’s annoying is that you have to measure out 1 gram of powder. It’s about half a teaspoon, but it’s difficult to get a consistent measure.

Quick Facts:

  • Chaga Extract : 143 mg
  • Cordyceps Extract : 143 mg
  • Lion’s Mane Extract : 143 mg
  • Maitake Extract : 143 mg
Pros
  • Combines proven mushroom extracts to impact the health of nerve cells
  • Also seems to work great to boost your immunity
  • The powder mixes easily with water or can be added to a smoothie
Cons
  • Measuring 1 gram of powder can be a bit difficult

4 - Mushroom Design

CTA of Mushroom Design
Effectiveness
4.7
Ingredients
4.8
Price
4.6
Overall Score 4.7
4.7

Here is another one of the cognitive enhancers that focuses on a blend of medicinal mushrooms that all have a positive effect on nerve cells.

One of the mushroom species that stood out for us is Reishi. Scientists have identified it as having a positive effect on stimulating immune cells [4].

And while the dosage of the mushrooms is great, we just found it difficult to order as it's often out of stock with major online retailers.

Quick Facts:

  • Maitake Mushroom : 200 mg
  • Reishi Mushroom : 200 mg
  • Shiitake Mushroom : 200 mg
Pros
  • High-quality mushroom supplement with multiple health benefits
  • Positive results for brain health and boosted immune system
  • Comes in a single capsule that is easy to swallow
Cons
  • It’s often out of stock making it difficult to keep up a steady supply

5 - Stonehenge Health Dynamic Mushrooms

CTA of Stonehenge Health Dynamic Mushrooms
Effectiveness
4.7
Ingredients
4.8
Price
4.6
Overall Score 4.7
4.7

Here’s another one of the interesting mushroom supplements with proven nootropic benefits.

Our testing team highlighted that this mushroom extract made them a lot more focused and motivated when it came to working and studying.

One of the nootropic mushrooms in this product is called Chaga, and it typically grows on birch trees.

It has not just been linked to boosting your immune system to fight cancer, but research suggests that it has a significant impact on cognitive functions [5].

Quick Facts:

  • Lion’s Mane Mushrooms : 1,000 mg
  • Chaga Mushrooms : 100 mg
  • Maitake Mushrooms : 100 mg
  • Shiitake Mushrooms : 100 mg
Pros
  • Combines several proven mushroom species
  • Seems to work great for improved focus and motivation
  • Comes in vegetable capsules suitable for vegans
Cons
  • The capsules are a bit larger than others we tested

6 - Poria Mushroom

CTA of Poria Mushroom
Effectiveness
4.7
Ingredients
4.7
Price
4.3
Overall Score 4.6
4.6

Next on our list of recommended mushroom supplements is this Poria mushroom extract.

Our testing team highlighted that they felt less stressed and fatigued, allowing them to focus better on work and study later in the day.

One meta-study identified that there is significant scientific evidence to suggest that Poria extract can help your immune system by boosting immune stimulators while at the same time limiting immune suppressors [6].

Quick Facts:

  • Poria Extract : 500 mg
Pros
  • Certified organic ingredients for high purity and quality
  • Comes in small capsules that are very easy to swallow
  • Great for stacking with Lion’s Mane to further promote brain health
Cons
  • It’s quite expensive compared to the other mushroom species above

7 - Mushroom Design

CTA of Mushroom Design 2
Effectiveness
4.7
Ingredients
4.6
Price
4.5
Overall Score 4.6
4.6

Here is another one of the mushroom supplements with a great blend of different species. And the company has also added a wide range of vitamins, including B complex, C, D, and E.

These, combined with Lion’s Mane, seem to have a good effect on your immunity. But there is also evidence that it can help to reduce inflammation in the bowels as well [7].

Our testing team liked these nootropic mushrooms for their effect on overall mood and happiness, and all of them found it helped them stay a lot more focused on work.

Quick Facts:

  • Cordyceps : n/a
  • Lion’s Mane : n/a
  • Turkey Tail : n/a
  • Agarikon : n/a
Pros
  • Positive effects on focus and motivation to stay on target
  • It may also help with autoimmune-related inflammatory reactions
  • Comes with a wide range of vitamins for boosted immune function
Cons
  • You’ll need to take two larger-than-average capsules

8 - Live Ultimate Shrooms

CTA of Live Ultimate Shrooms
Effectiveness
4.6
Ingredients
4.7
Price
4.5
Overall Score 4.6
4.6

Live Ultimate has put together a formula of organic medicinal mushrooms that seems to deliver brain power along with improved stress levels and mood, based on the feedback we got from our testing team.

The included Reishi mushroom has been shown to have an effect on nerve growth factor (NGF), which can significantly improve the health and functioning of your nervous system [8].

Quick Facts:

  • Reishi Mushroom : 450 mg
  • Cordyceps Mushroom : 450 mg
  • Chaga Mushroom : 450 mg
  • Maitake Mushroom : 300 mg
Pros
  • Organic certified ingredients make this a high-quality product
  • A great blend of proven ingredients for brain health benefits
  • No flavor from the powder when mixed with smoothies or other drinks
Cons
  • The powder doesn’t seem to be the easiest to mix with water

9 - FreshCap, Ultimate Mushroom Complex

CTA of FreshCap, Ultimate Mushroom Complex
Effectiveness
4.6
Ingredients
4.7
Price
4.5
Overall Score 4.6
4.6

FreshCap is another product with purely organic medicinal mushrooms where our clients said they felt a lot less stressed and anxious, especially during busy parts of a workday.

One ingredient that my nutritionist highlighted is Turkey Tail extract, which doesn’t just improve the health of the brain and nervous tissue, but may also help to prevent cancer [9].

The only downside she highlighted was that you might need more than two capsules to get a significant boost due to a lower dosage.

Quick Facts:

  • Maitake Extract : 167 mg
  • Chaga Extract : 167 mg
  • Turkey Tail Extract : 167 mg
  • Reishi Extract : 167 mg
Pros
  • Positive test results for reduced stress and anxiety levels
  • Organically sourced ingredients seem to provide higher purity
  • Available in large bottles to last you for months
Cons
  • You might need to take more than two capsules to get the best benefits

10 - Om Brain Fuel

CTA of Om Brain Fuel
Effectiveness
4.5
Ingredients
4.6
Price
4.4
Overall Score 4.5
4.5

The final one of our recommended mushroom supplements is this Om Brain Fuel, which focuses on just two types of mushrooms with proven benefits for the brain.

While it’s unclear how much Reishi is in the formula due to a proprietary label, this is one ingredient with a wide range of benefits, including potential impacts on cancer [10].

“Reishi mushroom has been used to help enhance the immune system, reduce stress, improve sleep, and lessen fatigue.” - Christine Mikstas, RD, LD at WebMD.com

I just wish the company published the exact amounts, as it would be a good product to stack with other nootropics.

Quick Facts:

  • Lion’s Mane : n/a
  • Reishi : n/a
Pros
  • Organically certified ingredients provide a higher purity level
  • You can easily spread out the three capsules a day for longer-lasting effects
  • Comes with added folate that can boost red blood cell production
Cons
  • The label lists a proprietary blend that makes stacking very difficult

Buyer’s Guide

A woman helping people online buy nootropics

Who Should Take Mushroom Nootropics?

Anyone who wants to achieve a boost in brain health and function should consider taking mushroom nootropics.

These nootropics are generally safe to take, and allergic reactions and side effects are rare.

These mushroom supplements can also help to boost your mood and focus levels making it easier to get through a busy day at work or with children. 

And if you struggle with stress and mood issues, then nootropics could be the simplest solution for you.

Related Articles:

Who Shouldn't Take Mushroom Nootropics?

Anyone who is on prescription medication for mental health issues shouldn't take mushroom nootropics without first speaking to a doctor.

While mushroom supplements don’t have major side effects, they could interact with certain drugs.

And your doctor should also know that you might be getting improvements from natural ingredients that might require an adjustment to your medication dosage.

“If you're considering trying nootropic supplements, you should talk it over with your doctor first. As with all supplements, you’ll want your doctor to let you know about any health risks, like effects on any conditions you have or medications you take.”

- Dan Brennan, MD at WebMD.com

It’s always better to be on the safe side with such medication.

Ingredients & Dosage

Here are a few ingredients you want to look out for in mushroom supplements:

  • Chaga Extract
  • Cordyceps Extract
  • Lion’s Mane Extract
  • Maitake Extract
  • Reishi Extract
  • Turkey Tail Extract

However, the one mushroom that has the most scientific evidence for improved brain function and health is Lion’s Mane.

And you want to look for a dose of 500 mg or higher to get the best effects.

FAQs

Which Mushroom Is Best For The Brain?

Lion’s Mane mushroom is best for the brain and has been extensively studied. It’s common in traditional medicine, and modern scientists have shown a link to multiple brain function improvements [11].

Are Shiitake Mushrooms Nootropic?

Yes, Shiitake mushrooms are nootropic and good for the brain. Some scientists have gone so far as to say that it can even counteract cognitive impairments from diseases [12].

Choose The Right Mushroom Supplements

Out of all the best mushroom supplements, the one we keep going back to for recommendation is the Lion's Mane Mushroom from Nootropics Depot.

It seems like the quality and dosage are ideal, and our testing team revealed significant improvements in concentration, focus, and motivation.

It’s also the easiest one of the lot for stacking with other nootropics, giving you a lot more flexibility when it comes to dietary supplements for your overall health and well-being.

Order your first supply today and see how much it can improve your life within a couple of weeks.

Our #1 Recommendation

Nootropics Depot Lion’s Mane Mushroom

CTA of Nootropics Depot
Effectiveness
4.9
Ingredients
4.9
Price
5.0
Overall Score 4.9
4.9
Pros
  • Great results for mental clarity and cognitive health
  • Positive scientific data on boosted nerve growth factor
  • Suitable for vegans as it comes in veggie capsules
  • Comes in large bottles of 180 capsules
  • Get the BEST PRICE until the end of January
Cons
  • Some people find the capsules a bit large
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