Supplements Considered 36
Hours of Research 109
of Research
Reviews Examined 84
Experts Interviewed 15
Connor Sellers
Published by Connor Sellers
Fact checked by Donald Christman, BHSc FACT CHECKED
Last updated: May 29, 2021

We’ve worked with people of all ages, and there are a few supplements that we always explore for some of our older clients.

One type of supplement that has gained more attention in the nutrition world is designed to boost nicotinamide adenine dinucleotide (NAD) levels.

There will be no rewards for being able to pronounce it, so from here on, we’ll just call it N A D.

Some research suggests that this supplement may help with anti-aging and life extension, but we were more interested in the immediate effects of it on energy levels.

So we teamed up with a few clients to test some of the best NAD supplements and check their health benefits.

Our Top NAD+ Supplements

1 - Tru Niagen Nicotinamide Riboside (Editor's Choice)

tru niagen product

Tru Niagen is the product that our clients said might be the most effective. The specific source and type of nicotinamide were chosen based on scientific trials that showed positive results.

We noticed quite a few changes in clients in just about two weeks, which also might make this one of the faster-acting nad supplements.

Check out our full Tru Niagen review.


  • Nicotinamide Riboside 300 mg
  • Claims to help reduce metabolic stresses
  • The formula was chosen based on results from human clinical trials
  • Positive reviews about effects kicking in after two weeks
  • Available with great subscription discounts
  • The anti-aging effect may take longer to become visible

The only thing you might not notice immediately is the effect on physical aging, which could take several months.

2 - Toniiq NMN

Toniiq NMN

This NMN supplement from Toniiq claims to be one of the stronger options available, which could be a good choice for older people trying to achieve a more significant boost.

The product has also been designed to be stable at room temperature, which means you won’t need to keep it in the fridge.


  • NMN 500 mg
  • UltraNMN formula claims to be of the highest grade
  • Claims to be shelf stable, so doesn’t require refrigeration
  • It’s an affordable bulk order option
  • Requires two capsules daily for the full dose

Just keep in mind that the larger dose will require taking two pills per day, which might not suit people who don’t like swallowing capsule supplements.

3 - Thorne Research ResveraCel

Thorne Research ResveraCel

Here’s another product where we saw quite a few positive comments online about how it could improve the levels of NAD precursors. This would explain why quite a few older people seem to show signs of improvement within weeks.


  • Nicotinamide Riboside 300 mg
  • Seems to work well for stabilizing aging effects at the cell level
  • Batches go through multiple rounds of testing to ensure quality and purity
  • May also support healthy heart and brain function
  • The capsules are almost an inch long, making them a bit difficult to swallow

These capsules are possibly the largest we encountered, so keep that in mind before ordering.

4 - NMN Plus

NMN Plus

This supplement stood out because the company made it clear that they kept the formula as simple as possible to avoid any use of allergens or fillers.

Users have reported that they feel a better mental attitude and improved brain energy [2] upon taking this supplement.

We also noted that people are saying their sleep patterns have improved.


  • NMN 300 mg
  • Uses a simple formula with no additives or fillers
  • Could improve your mood and sleep pattern
  • Seems to have positive reviews about the boosted brain function
  • Some of the benefits might take more than 30 days to kick in

We just found that some health benefits didn’t show up until consistently using it for about a month.

5 - eSquared Nutrition Nicotinamide with Resveratrol

eSquared Nutrition Nicotinamide with Resveratrol

We thought this supplement has a clever name. If you’re a science nerd, you might notice the hint at Einstein's formula.

A few of our clients reported a significant change in their energy and sleep patterns upon using this product.

People also like the long term effects that might reduce some natural aging in the body [3].


  • Nicotinamide 500mg, Resveratrol 100mg
  • Might help boost energy levels as well as immunity
  • Claims to be a flush-free product to avoid side effects
  • Seems to provide good anti-aging and anti-inflammatory properties
  • Resveratrol is not suitable for people undergoing blood-thinning medication

The important thing to keep in mind with resveratrol is that it’s not suitable for some types of medication.

6 - MAAC10 NMN


We like that MAAC10 takes consistency and quality seriously. Every batch of this supplement is tested to ensure you always get the right grade and concentration.

You also have the option to ask for your money back if you’re not satisfied with the changes it might bring to your life.


  • NMN 125 mg
  • Claims to be more stable and effective than nicotinamide riboside
  • Tested for 99% purity and higher-grade content
  • Comes with a 60-day money-back guarantee for peace of mind
  • The dosage is quite low, so may not be as effective as the others

I would say that this isn’t the best option if you’re looking to make a more significant change in your body as the dosage is quite low.

7 - Ultra Health NAD+

Ultra Health NAD+

Ultra Health NAD+ is among the cheaper NAD supplement products available. However, that doesn’t mean it uses inferior ingredients that aren't backed by science.

We saw some blood test results from users that showed an increase in NAD levels after a month of consistent intake.


  • Nicotinamide Riboside 300 mg
  • Claims to target cellular level immunity to help with age-related problems
  • Test results show it may be effective at triggering NAD precursors
  • It’s a cheaper option but still seems to work well
  • Requires taking two capsules per day

However, you will need to take two capsules for the full dose.

8 - HPN Nutraceuticals Nicotinamide Riboside

HPN Nutraceuticals Nicotinamide Riboside

This HPN supplement was also positively reviewed by many users for all aspects of life. Better physical performance, mental boosts, and improved immunity were all mentioned.

It also claims to help reduce metabolic disease issues that could often leave you feeling sluggish.


  • Nicotinamide Riboside 250 mg
  • Seems to be working well for improving mood and brain function
  • Claims to enhance your natural metabolism for more effective energy production
  • Positive comments about measurable increases in levels of NAD
  • The capsules are pretty big and may take getting used to

You might need to get used to the size of the capsules, as they aren’t the easiest to swallow.

9 - Gene Formulas Nicotinamide Riboside

Gene Formulas Nicotinamide Riboside

The last of our best recommended NAD supplements is from another company that has kept the formula as simple as possible.

It should support higher NAD levels within about four weeks, which is a bit longer than other products but still a decent time frame for an overall increase.


  • Nicotinamide Riboside 250 mg
  • Keeps the formula simple, so you know what you get
  • Positive comments about boosted energy levels and mood
  • Doesn’t contain allergens and fillers that might cause side effects
  • Some reports about missing pills in bottles

We did notice that a few people have complained about the bottles not containing the right number of pills.

10 - Vivalifer NMN Super Nicotinamide Mononucleotide

Vivalifer NMN Super Nicotinamide Mononucleotide

Vivalifer NMN is probably one of the best NMN supplements out on the market.

Some studies show that the mononucleotide type used in this product might help with getting better sleep [1]. That might have significant rejuvenating benefits within just a few days.

We also saw quite a few comments where people said they had their NAD levels tested and that there was a measured improvement after taking it for several weeks.


  • Nicotinamide Mononucleotide (NMN) 500 mg
  • Positive comments about boosted NAD+ levels providing more energy
  • Free from common allergens and artificial additives
  • Seems to support better sleep cycles
  • The capsules are not the smallest to swallow

The only thing we found is that the capsules are a bit on the large side.

“There’s a complex, two-way relationship between NAD and circadian rhythms, one that influences sleep-wake patterns and other important physiological processes, including metabolism.”


- Dr. Michael Breus, Sleep Specialist


Is Nmn Better Than Nad?

No, NMN isn’t better than NAD, as they are completely different substances. NMN works as a precursor to NAD, and studies have shown that it’s an effective way to increase NAD levels in your body.

At What Age Does Nad Decrease?

NAD levels decrease from a young age after puberty. But the most notable reduction comes after age 50 when measured levels might drop as much as 50%. This is why it’s a commonly recommended supplement for older people.

The Best NAD+ Supplement Is...

All of our testing has made us conclude that Tru Niagen nicotinamide riboside is the best supplement to buy. It seems to provide the best form for higher absorption, and its success is backed by science.

Our clients have all had positive things to say about it and their performance at the gym and motivation to exercise more have all improved.

You should also try to take advantage of the bulk discounts available, which most other products don’t offer.

And make sure you report back to us how quickly you think it resulted in some improvements for your body.

tru niagen product

Tru Niagen Nicotinamide Riboside

Our #1 Recommendation

  • Claims to help reduce metabolic stresses
  • The formula was chosen based on results from human clinical trials
  • Positive reviews about effects kicking in after two weeks
  • Available with great subscription discounts
  • Get the BEST PRICE until the end of June
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