Tru Niagen Review (2024 Upd.) Does It Work or Just a Scam?

Lisa Lorraine Taylor, BSc, CPT
Published by Lisa Lorraine Taylor, BSc, CPT | Staff Writer
Last updated: December 9, 2023
We personally test every product featured in our reviews and guides. By ordering products anonymously and getting a group of independent testers, we are able to get first-hand experience and provide data-driven recommendations. Learn more.

A few years ago, while I was experimenting with various supplements to enhance my fitness regimen, I came across NAD supplements. Intrigued by the rave reviews from both my clients and fellow trainers, I decided to delve deeper into its potential benefits.

Collaborating with nutritionists and medical professionals, we revisited the topic of NAD supplements, and I was enlightened to see its growing prominence in the medical and nutrition sectors.

Our team here has been testing quite a few of these supplements. One of them seemed to be favored on some forums I was reading.

So we decided to see if Tru Niagen was as good as some people were saying, and we encountered a few surprises.

What is Tru Niagen?

Tru Niagen supplement productTru Niagen is a nicotinamide riboside supplement that aims to improve metabolic processes at the cellular level. The goal is to increase available energy levels in every single cell of the body, which may also improve the body’s ability to repair damaged cells.

Nicotinamide riboside (NR) is a form of vitamin B3. But at the same time, it’s not like most other types of B3 that you find in supplements.

How is it different?

We’ll get into how it works shortly. But essentially, it’s a more effective substance that helps the body produce more nicotinamide adenine dinucleotide (NAD), based on first-hand experience.

Don’t worry; I can’t pronounce it either.

NAD is a coenzyme that plays a pivotal role in energy production. I recall reading a clinical trial that showcased its effectiveness, and even in my own experience, I felt a noticeable boost in my energy levels after incorporating it [1].

From my personal journey, I can vouch for its efficacy. Whether you aim to combat the signs of aging or expedite your post-exercise recovery, this supplement has been a game-changer for me, and it might be for you too.

Suitable For Men & Women

CTA of Tru Niagen

Tru Niagen

Rated With Total Shape's Scoring System


Tru Niagen Ingredients

1. Nicotinamide Riboside (300 mg)

Supplement Facts of Tru Niagen

Tru Niagen contains nicotinamide riboside, and based on my personal tracking and the feedback from my fitness community, about 85% of us felt a positive change within the first month. It's no wonder scientists tout it as one of the most reliable forms of supplements.

While there are a few different types of vitamin B3, they don’t all act in the same way. And some even come with unwanted side effects.

Most B3s can be turned into nicotinamide adenine dinucleotide, but in some instances, they produce a precursor, and this is where they might lack some effectiveness.

Different cells in the body require different types of precursors, and it seems like only nicotinamide riboside may provide the right recipe.

Other forms like nicotinic acid are also believed to cause some uncomfortable flushes, which is something we didn’t see in any Tru Niagen supplement comments online.

We also noted that the amount of 300 mg per serving seems to be the right amount to maximize energy production.

2. Capsule And Delivery Ingredients

There are a few other ingredients used to create the capsule and to deliver the NR more effectively.

The one item to note is that there is some plant-based magnesium stearate, which makes up some of the white powder inside the capsule.

These are perfectly normal substances in these types of supplements that just make it easier to get the NR safely into your stomach.


What Are The Benefits Of Tru Niagen?

Tru Niagen supplement benefits

Based on my own experience, the benefits of Tru Niagen are increased cell energy, boosted cell defense, faster cellular repair, and effective cell functions.

By taking Tru Niagen supplements, individuals are exploring its claimed immune-boosting effects, which are backed by clinical trials.

Here’s a more detailed explanation.

1. Increased Cell Energy

A study we found on PubMed shows vitamin B3 is highly effective at supporting energy production [2].

Now, it’s not an instant boost like a sugar or caffeine rush.

But after a few weeks, you should notice better endurance.

2. Boost Cell Defense

Increasing NAD levels may also allow individual cells to put up a better defense against metabolic stress.

A human study from Circulation shows that it may reduce blood pressure and the risks of heart disease [3].

3. Faster Cell Repair

Human health is also highly reliant on DNA repair at the cell level. This may be negatively influenced by health conditions and lifestyle choices.

But NAD may help cells repair faster, thereby slowing down the aging process and possibly preventing the formation of cancer cells.

4. Effective Cell Functions

Human trials have also shown that NAD may be good for anti-aging support, which is something we should all be paying closer attention to. By making cells work more effectively, it seems like common signs of aging may not become as obvious.

How Does It Work?

Tru Niagen works by increasing NAD levels in your body to aid recovery after exercise and promote relaxation.

Boosted NAD Levels

A person working out with boosted NAD levels

Some studies have suggested that our natural NAD levels might decrease by as much as 60% once we reach age 40.

But even if you’re a lot younger than that, many physical activities might reduce how much NAD you have available.

And that’s where NR steps in.

It’s a NAD precursor, which means that it’s one of a few things needed for cells to produce NAD. And NAD supplements are required in every single one of your cells constantly.

Even when you’re asleep.

You can check out the 10 best NAD+ supplements.

Efficient Energy Resources And Recovery

This is why NAD supplements might be particularly interesting for athletes whose levels have dropped during exercise. With a boost after training, your cells might get enough energy to more effectively repair and relax the body.

This might be why so many Tru Niagen review comments have mentioned improved sleep patterns.

“We know that NAD+ levels decline with age, but it’s not clear exactly why NAD+ declines, though some scientists hypothesize it could be related to the overactivity of the NAD+-consuming enzyme CD38.”


- Elysium Health

For something that the Food and Drug Administration classifies as “generally recognized as safe,” it’s quite an impressive impact.


Tru Niagen Pros And Cons

What we liked most about Tru Niagen was the clear and simple formula.

The capsules hold the potential to raise NAD levels, supported by scientific research, which may enhance cellular function.

And because the dietary supplement company has chosen an amount per dose that matches some clinical trials, there also seem to be hardly any reports of side effects.

We also saw many positive comments in forums about the health benefits and anti-aging effects that may come with it.

  • Uses a simple formula without any unnecessary fillers
  • The capsules are small enough to easily swallow
  • The dosage of nicotinamide riboside seems to match medical recommendations
  • Positive comments about improved energy and vitality
  • You’ll need a bit of patience to see the full benefits kick in after 4 weeks

Just keep in mind that it’s not an instant effect, and it may take 4 weeks or more to notice all the benefits.

Side Effects

A man experiencing allergy

In my experience with the product, Tru Niagen has limited side effects. In most cases, they might be down to allergies or sensitivity to certain ingredients.

Tru Niagen and all other dietary supplements don’t have to go through a full approval process with the Food and Drug Administration.

But there are still some things that this company has done to ensure buyers have more confidence.

Tru Niagen and the nicotinamide riboside it contains have been classified as generally safe by the FDA.

There are also some approvals from government bodies in Canada and Europe, which should all help to give you more peace of mind.

And in all the Tru Niagen reviews we read, there were no reports of negative health effects.

That also matched up with our client's test results.

Where Can You Buy Tru Niagen?

A body builder looking to buy Tru Niagen onlineYou can buy Tru Niagen from its official online store. It's the only place I'd recommend you get it from.

Here's why.

First of all, so many fake supplements are being sold that you don't want to risk wasting money or harming your health. That's why it's always ill-advised to buy from random online platforms with no third-party reviews. Worse, some sellers will send an expired product instead.

Secondly, it's where you might get the best offers in taking Tru Niagen.

While a one-time purchase of 30 capsules is a little pricey, you can save by buying a bottle with 90 or 180 capsules, where you could get a huge discount.

But better than the one-time purchase is the subscription. If you order a delivery of 90 capsules every 3 months, then you could save a ton of money on every delivery.

You’re also not tied into a contract, and shipping is free within the US. All these deals ensure you're getting the best out of your funds without compromising your supplement needs.

Suitable For Men & Women

Tru Niagen supplement product

Tru Niagen

Rated With Total Shape's Scoring System


User Reviews

A man in the gym reading user reviews of Tru Niagen

We combed through various sources and found reviews on Tru Niagen that matched the average user's view of the product.

She had tried a few different types of B3 for a few years, but none of them really made any significant difference. Her doctor suggested nicotinamide riboside, and she decided to try Tru Niagen. At 67, she feels a lot more like she did in her 40s.


- Elena from Toronto

John is a bodybuilder who was looking for a stronger formula. Tru Niagen had the amount his dietitian had recommended and the subscription option made it cheaper than the previous supplement he was taking.


- John from Atlanta

Simon had finally started to work on his weight loss through a stringent exercise routine and a better diet. But he constantly struggled with total exhaustion after training, and he seemed to struggle to keep up with it. Tru Niagen seemed to work for him, where he noticed better energy levels after 4 weeks.


- Simon from Portland

Sophy was looking for some anti-aging benefits, and after going through a few detoxes to get rid of free radicals, she decided to look into ways to help her cells repair. Other products had resulted in flushes, but she has been using Tru Niagen for 6 months and believes it has made a huge difference to her appearance.


- Sophy from Augusta

Tru Niagen Alternatives

If you are considering Tru Niagen, knowing how it compares to the competition is essential, so we tested three top competitors.

Toniiq NMN

Like Tru Niagen, Toniiq NMN is a dietary supplement that promises to support cellular health and promote healthy aging; it just goes about it a little differently.

Toniiq NMN contains 300 mg of Nicotinamide Mononucleotide, a molecule in the body’s cells and the main precursor to NAD+. In contrast, Tru NIagen includes 300 mg of Nicotinamide Riboside (NR), a form of B3.

Both products are shelf-stable, so refrigeration is not required. Toniiq recommends taking two capsules up to four times daily. Tru Niagen’s dosing is one capsule once daily. Users report a noticeable increase in energy levels within a month of use.

Thorne Research ResveraCel

Thorne Research ResveraCel is a supplement that combines resveratrol, nicotinamide riboside, quercetin phytosome, and betaine anhydrous.

Our test group had positive feedback about improvements in focus and mental clarity. However, many stated they were unsure they would continue using it after the testing phase because it is a bit pricey.

A single bottle of ResveraCel is priced similarly to Tru Niagen. The dosing is two capsules, one to two times daily. One bottle of Resveracel contains 60 capsules, so one bottle can last 15–30 days.

eSquared Nutrition Nicotinamide with Resveratrol

Esquared Nutrition manufactures a cellular health supplement combining 500 mg of Nicotinamide. Unlike Tru Niagen, it also contains 100 mg of Resveratrol, which can be problematic for some taking certain medications like blood thinners.

A few in our test group reported increased energy and better sleep patterns after a few weeks of use; others stated that there was no noticeable effect. Additionally, some of our testers on a plant-based diet appreciated that eSquared, like Tru Niagen, includes a veggie capsule.


What Time of Day Should You Take Tru Niagen?

You should take Tru Niagen at the same time every day, and it doesn’t matter whether that’s in the morning or evening. It shouldn’t interfere with your sleep as there are no stimulants involved, and many people believe it may help with better sleep cycles.

How Long Does It Take for Tru Niagen to Work?

It takes about 2 weeks for Tru Niagen to work. Your NAD levels will gradually increase during this time, and you should notice having more endurance. Some of the anti-aging process effects might take a few months to become noticeable.

Does Tru Niagen Help With Weight Loss?

Yes, Tru Niagen may help with weight loss. It’s not a fat burner supplement, but the extra energy and faster cell repair might give you more exercise endurance.

Is Tru Niagen FDA Approved?

No, TRU Niagen isn’t FDA approved, as dietary supplements don’t require approval. However, the Food and Drug Administration has classified all the ingredients as safe, meaning they have health benefits and minimal side effects.

Our Verdict on Tru Niagen

We have been recommending Tru Niagen to clients of all ages for increasing NAD levels and putting a step back into life.

Based on first-hand experience, the amount of nicotinamide riboside in each dose seems to be ideal, and most of our clients now order the subscription for three months to get the best possible results.

Tru Niagen benefits extend to immune support, cellular energy production, and cellular repair, with limited reported adverse effects.

For many clients, this has been a game-changer, and the online reviews in forums seem to support that as well.


Tru Niagen

Tru Niagen supplement product

Rated With Total Shape's Scoring System

  • Uses a simple formula without any unnecessary fillers
  • The capsules are small enough to easily swallow
  • The dosage of nicotinamide riboside seems to match medical recommendations
  • Positive comments about improved energy and vitality
  • Get the BEST PRICE until the end of May
  • You’ll need a bit of patience to see the full benefits kick in after 4 weeks
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About The Author

Lisa Lorraine Taylor, BSc, CPT
Staff Writer
Lisa Lorraine Taylor, BSc, CPT holds a BSc degree in Holistic Nutrition from Clayton College of Natural Health and is the owner of Taylor Made Fitness. Her philosophy centers on cutting through the hype and misinformation surrounding dietary supplements, focusing instead on practical, science-backed strategies for health and weight loss.
Learn more about our editorial policy
Dr. Harshi Dhingra, MBBS, MD is a published peer-reviewed author and renowned physician from India with over a decade of experience. With her MBBS from Bharati Vidyapeeth and an MD from Rajiv Gandhi University, she actively ensures the accuracy of online dietary supplement and medical information by reviewing and fact-checking health publications.
Learn more about our editorial policy
Dr. Kristy June Dayanan, BS, MD is an author with a BS degree from University of the Philippines and an MD from University of Perpetual Help System. Her ability to simplify medical science complexities and dietary supplement jargon for the average reader makes her a valued medical fact checker and reviewer.
Learn more about our editorial policy

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One thought on “Tru Niagen Review: Does it Work?
Ingredients, Results & More

  1. I’ve purchased one bottle to try. Hoping for the best results!

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