Xenadrine Review (2025 Updated) Legit or Just a Scam?

Supposedly, this is one of the more powerful Xenadrine supplements, and it includes quite a lot of ingredients compared to Xenadrine Ultimate.

1 - Caffeine Anhydrous: You might think of this as just boosting mental focus, but caffeine may also act as a potent thermogenic. It may boost your metabolic rate even when resting to burn off more calories [6].

2 - Myristica Fragrans:  Studies have shown that this nutmeg seed can cause good weight loss effects [7].

3 - Phoria Longana: There may be a link with this ingredient to appetite control, but without clinical trials to confirm it, we wouldn’t recommend this as a suitable weight loss ingredient.

4 - Teacrine: While researchers did not confirm that it has fat-burning properties, it has been shown to reduce low-density lipoprotein (LDL), also known as "bad cholesterol" [8].

5 - MCT Oil: I personally take MCT oil on a regular basis, but its main benefit is for brain function. I couldn’t find any evidence that it would help you lose more weight.

6 - Rhodiola Extract: This is an interesting ingredient and one that we did find scientific support for. It seems like it may directly target belly fat [9].

7 - B Vitamins: These are generally a good idea for energy levels and to support your cognitive function [10]. However, traditional methods like multivitamins would bring the same positive effects.

8 - CLA: Conjugated linoleic acid does have a close link to weight loss, supported by studies [11]. It’s also becoming a lot more common in these types of supplements.

9 - C. Canephora Robusta: Xenadrine claims that there are human studies to support that this ingredient may lead to significant weight loss. But unfortunately, we weren’t able to verify that these studies used a control group.

This is one of the company’s original products, and it’s focused on just a few ingredients.

1 - Turmeric: Turmeric has been studied a lot, and there is plenty of evidence to support that it works as a thermogenic similar to caffeine [12].

2 - ALA: Alpha lipoic acid is important for cells to process glucose energy. In theory, a higher supply may ensure that released fat energy doesn’t hit a bottleneck in different body cells [13].

3 - CLA: We mentioned a study above regarding CLA, and it has been shown to potentially support weight loss in obese people.

4 - MCT Oil: This is great for providing a brain energy boost, but we have struggled to justify it here for a weight loss effect [14].

5 - Bioprene: Black pepper extract may help slow down your body’s ability to form new fat cells. That might be an indirect weight loss effect that helps users maintain their weight [15].

This is another simple product and one that we thought might have the highest chances of success.

1 - Turmeric: The Asian spice is very common in diet pills, and the products that we have had the most success with all included turmeric. It’s also suitable for taking over long periods as it doesn’t tend to cause problems.

2 - ALA: We mentioned this one above, and we would say that it’s a positive ingredient to ensure all the released energy from fat can be processed in your body. That increased energy supply might hit a bottleneck which could then slow down the release of fat cells.

3 - Apple Cider Vinegar: Some studies have shown that apple cider vinegar might influence body fat [16].

4 - Garcinia Cambogia: I regularly take Garcinia Cambogia in cutting phases, but I find it’s more helpful for appetite suppression than actually burning fat. It’s still a good ingredient to have on your side.

5 - Bioprene: We highlighted above that this extract from black pepper plants is generally considered to be a good ingredient. There is a fat blocking effect linked to it that may be more effective than the green coffee bean and caffeine.

Neuroheat was the last product we looked at, and because of its hyped-up name, we were a bit suspicious.

1 - Choline: Choline is a trace mineral that studies have linked to helping with fat release [17]. It’s also generally classed as safe and may also impact your appetite in a positive way.

2 - Huperzine-a: This is one of those mysterious ingredients where nobody is really sure what it is, and details are hidden behind a proprietary formula. And without peer-reviewed studies and trials, we would dismiss this ingredient as unproven.

3 - C. Canephora Robusta: We mentioned above that this is one of the top scientifically proven ingredients claimed by Xenadrine, but all of our research showed that the few existing studies shouldn’t be taken at face value.

4 - Caffeine Anhydrous: The dose is quite high at 220 mg, which is more than a large cup of coffee and probably too much caffeine to make some people jittery.

5 - Satsuma Orange: During our research, we found a few references to the benefits of this orange extract, but none of those were able to reference clinical tests that confirmed that it would help [18].

6 - Grains Of Paradise: We came up empty for any kind of scientific support for using it. That doesn’t mean that they don’t work, but the products we have recommended to clients all include proven ingredients.

We also want to add a few details we got from online Xenadrine reviews.

"Cathy had a goal of losing weight after having children, and she took Xenadrine Ultimate for eight weeks. She thought there was a benefit from the first pill, but she hit a plateau after four weeks and ultimately switched to a different product."

- Cathay, Delaware

"Jason kept the same exercise plan and diet but found there was practically no difference in his progress. He also increased to two pills per dose and still didn’t see a difference."

- Jason, New York