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10 Best Supplement Stacks for Weight Loss (2022 Updated)

Connor Sellers
Published by Connor Sellers
Fact checked by Donald Christman, BHSc FACT CHECKED

As a certified fitness coach, I’ve noticed that most of my clients reach out for fat-burning stacks when their goal is to lose pounds fast.

With the help of my dietitian, I dedicated my time to researching the best stack to burn fat.

I found a few stacks with ingredients that boost metabolic activity and energy and suppress appetite, among other important things.

Keep on reading for our top pre-workout fat-burning supplement stacks for fat loss.

Editor's Choice
CTA of Transparent Labs Fat Burning Essentials Stack
Transparent Labs Fat Burning Essentials Stack
Effectiveness
5.0
Ingredients
5.0
Price
4.9
Overall Score 5.0
5.0
Click For Best Price
#2nd Best Choice
Crazybulk Bulking Stack
CrazyBulk Bulking Stack
Effectiveness
5.0
Ingredients
4.9
Price
4.8
Overall Score 4.9
4.9
Click For Best Price
#3rd Best Choice
CTA of PhenQ and Gorilla Mode
PhenQ and Gorilla Mode
Effectiveness
4.9
Ingredients
4.8
Price
4.8
Overall Score 4.8
4.8
Click For Best Price

Our Top 10 Weight Loss Supplement Stacks (November 2022)

1 - Transparent Labs Fat Burning Essentials Stack (Editor's Choice)

CTA of Transparent Labs Fat Burning Essentials Stack
Effectiveness
5.0
Ingredients
5.0
Price
4.9
Overall Score 5.0
5.0

This supplement stack contains caffeine that boosts your energy and increases your focus during a workout.

It also includes zinc, an important ingredient that keeps your workouts steady and aids in lean muscle building.

Typically, the pre-workout stacks help you burn fat 24 hours a day, boost your metabolic activity and immune function, and reduce cravings during the day [1].

What stood out to me the most was the chromium picolinate in the PreSeries LEAN pre-workout that's part of this fat loss stack. It helped me burn fat I couldn't otherwise shed with other ingredients.

I've read a lot of positive feedback regarding Transparent Labs Stack and found that it provided the fastest results.

With all these supplements, you could also start with the Transparent Lab Fat Burner, which is the biggest difference maker in the stack.

Pros
  • Features science-backed non-proprietary blends
  • Recommended for those who are sensitive to stimulants/caffeine
  • There are no artificial sweeteners or coloring
  • Non-GMO and gluten-free
Cons
  • Not suitable for people sensitive to caffeine

2 - CrazyBulk Bulking Stack

Crazybulk Bulking Stack
Effectiveness
5.0
Ingredients
4.9
Price
4.8
Overall Score 4.9
4.9

CrazyBulk carries a great assortment of top-rated oral steroid substitutes that function well throughout the cutting period.

They include clenbuterol, which effectively supplies oxygen to your muscle systems, dramatically improving your aerobic performance [2].

Other great components are Winsol and Anvarol, which deliver a fantastic energy boost, enhance strength, and are visceral fat burners.

After testing the CrazyBulk stack for weeks, my male friends said they felt an increase in stamina that enabled them to work out regularly and lose fat.

Pros
  • Maintains muscular strength during long exercises
  • Beneficially impacts protein synthesis in muscles for faster recovery
  • Contains a low amount of sugar and caffeine
Cons
  • Requires a reminder to take it at different times of the day

3 - PhenQ and Gorilla Mode

CTA of PhenQ and Gorilla Mode
Effectiveness
4.9
Ingredients
4.8
Price
4.8
Overall Score 4.8
4.8

Another awesome stack I tried was a combo of PhenQ and Gorilla Mode.

This fat burner suppresses hunger, food cravings, and binging and boosts metabolism, making you lose weight.

You require two scoops of Gorilla Mode pre-workout and two pills of PhenQ each day. You should never exceed the daily dosage.

The stack contains chromium, an essential fat-burner, and improves the body's metabolism of carbohydrates and protein [3].

I used half a dose of Gorilla Mode and two pills of PhenQ, and in three weeks, I was down by 9 lbs. I also experienced an increase in my stamina, which helped me push even harder.

"With enough chromium, muscle cells can enhance muscle building, less extra sugar is stored as fat, and excess fat can be burned as fuel."

- Harry Preuss, M.D.

Pros
  • The components are all-natural
  • Boosts metabolism
  • Provides a massive boost in nitric oxide (NO) levels
Cons
  • Not recommended for caffeine-sensitive people

For PhenQ:

For Gorilla Mode:

4 - Aphro D and PhenQ

CTA of Aphro D and PhenQ
Effectiveness
4.8
Ingredients
4.7
Price
4.7
Overall Score 4.7
4.7

This pre-workout stack approaches fat loss from five perspectives: fat burning, fat buildup, suppressed food cravings, endurance, and mood.

This approach enables the fat-burning supplement stack to provide multiple advantages for your objectives to lose weight and overall well-being.

However, be aware that it may take approximately a month of constant use to reap the full benefits, so be patient.

Some of my clients claimed to feel less hungry, which helped them eat less and lose around 4–6 pounds after a month and a half.

Pros
  • No harmful derivatives or adverse effects
  • Blocks the new fat production
  • Doctor-formulated and FDA-approved
Cons
  • Takes a bit longer to see the results

5 - Aphro D and Instant Knockout

CTA of Aphro D and Instant Knockout
Effectiveness
4.6
Ingredients
4.6
Price
4.6
Overall Score 4.6
4.6

This stack contains high-quality components like green tea, Schisandra berry, and vitamin D3 that suppress hunger, enhance testosterone levels, boost metabolism, and improve insulin sensitivity.

These benefits improve the way carbohydrates are processed and stored in your body.

Green tea is a fat-burning ingredient due to the presence of catechins known to be bioactive polyphenols. Catechins provide caffeine-like advantages, giving the stimulation necessary to finish your exercises, thus increasing fat oxidation by 16% [5].

Most of my male clients claimed they experienced a boost in their focus and strength that helped them lift better.

Pros
  • Eliminates oxidative stress
  • Contains natural ingredients
  • No side effects
Cons
  • Relatively expensive

For Aphro D:

For Instant Knockout:

6 - Leanbean and Powher

CTA of Leanbean and Powher
Effectiveness
4.4
Ingredients
4.5
Price
4.5
Overall Score 4.5
4.5

Numerous natural systems in the body are involved in fat burning.

And that's why the Leanbean and Powher fat-burning supplements for women are designed to stimulate multiple body processes, finally allowing them to burn fat.

The distinctive formula contains the appetite suppressant glucomannan.

It operates by causing swelling in the stomach that makes you feel full between meals, thus consuming fewer calories [7].

This women's supplement stack employs necessary ingredients in appropriate amounts, such as RedNite and tyrosine, to reduce adverse side effects.

Additionally, it contains a safe combination of natural thermogenic fat-burning minerals that improve your metabolic activity. Choline, for example, has been demonstrated to promote optimal fat metabolism.

After using this fat-burning stack for a month, my female clients claim that they lost 4–7 lbs, as it made them feel full during the day, thus consuming fewer calories.

"When taken before meals, glucomannan may lead to modest weight loss in overweight individuals, mainly by creating a feeling of fullness and reducing calorie intake."

- Atli Arnarson BSc, PhD

Pros
  • Natural healthy sources of caffeine
  • Boosts lean muscle growth
  • Easy to order
Cons
  • Not recommended for pregnant women

7 - Lean XT and Stim-Free Transparent Labs

CTA of Lean XT and Stim-Free Transparent Labs
Effectiveness
4.4
Ingredients
4.4
Price
4.5
Overall Score 4.4
4.4

This is an all-natural thermogenic fat-burning supplement stack for men. It has no caffeine or any other stimulant.

The products' potent mix was developed using the most efficient science-backed components, such as forskolin, n-acetyl l-tyrosine, and citrulline malate.

Combining these substances helps burn fat and maintain lean muscle mass.

In addition, this supplement stack increases your metabolism and reduces your appetite, leading to lower calorie consumption.

My caffeine-sensitive male clients liked this stack because it made them feel full most of the time, which helped them shed some weight faster.

Pros
  • Replenishes the body’s lost electrolytes
  • Non-stimulant, and vegan-friendly fat burner
  • Increases lean muscle growth with sustained resistance workout
Cons
  • The stack may cause bloating

For Lean XT:

For Stim-Free Transparent Labs:

8 - Instant Knockout and Gorilla Mode

CTA of Instant Knockout and Gorilla Mode
Effectiveness
4.4
Ingredients
4.4
Price
4.2
Overall Score 4.3
4.3

This stack includes cayenne pepper seeds containing capsaicin, a substance known for its beneficial impacts on metabolism, appetite suppression, and weight control.

It also boosts insulin sensitivity, resulting in greater energy and a reduced body fat percentage [4].

Other great ingredients include green tea extract for fat burning, glucomannan which makes you feel fuller, and caffeine anhydrous that stimulates your nervous system.

In addition, L-citrulline and vitamin B6 boost your energy, while huperzine A increases focus.

When it comes to the flavor and texture, I found the Gorilla Mode in this stack to be a little gritty, so it might take some time to get used to it.

Pros
  • Detoxifies the body of free radicals
  • No remarkable adverse effects
  • Suppresses hunger
Cons
  • The capsules are quite large

9 - PhenQ and Testoprime

CTA of PhenQ and Testoprime
Effectiveness
4.2
Ingredients
4.4
Price
4.2
Overall Score 4.3
4.3

Caffeine in this fat burner supplement stack suppresses your appetite and decreases hunger cravings, allowing you to stick to a healthy diet [6].

You may experience a boost in energy and endurance, reduced brain fuzz, increased muscular mass, and an enhancement in sexual prowess.

I loved this stack because it sharpened my focus and strength during a workout and allowed me to lose fat by curbing my hunger for extended periods.

Pros
  • Reduces brain fog
  • It is gluten, dairy, and soy free
  • Does not require a prescription
Cons
  • Not suitable for pregnant women and people under 18

10 - Leanban and Stim-Free Transparent Labs Pre-workout

CTA of Leanban and Stim-Free Transparent Labs Pre-workout
Effectiveness
4.2
Ingredients
4.2
Price
4.2
Overall Score 4.2
4.2

This pre-workout stack formula was developed to help with enhanced power, building muscle, improved mental and physical performance, and overall wellness.

It aids in the proper fat metabolism and enhances your energy, allowing you to train even harder.

This fat-burning pre-workout stack is additionally designed to help you lessen your food cravings.

It accomplishes this through the implementation of the fiber glucomannan.

I was able to lift heavier as the stack increased my energy and strength.

However, I did not shed as much weight as I did with Transparent Labs' fat-burning essential stack.

Pros
  • Reduces premature muscle fatigue
  • Maintains a stable blood sugar level
  • Doesn't contain stimulants
Cons
  • It may take about three months for some people to see results

Buyer's Guide: How We Chose the Best Supplement Stacks?

Close up shot of a gym trainer holding a clipboard

We decided to come up with a buyer's guide that will help you choose the best fat-burning stack.

We did our routine testing with the help of our clients; therefore, you will not waste your money on products that are not suitable for you.

Here is what we considered when making our list.

Product Synergy

We've given great consideration to how the specific elements of a stack function, not just on their own but as part of the overall nutritional picture.

If you're not careful about every aspect of your nutrition, you might be overlooking some potential benefits.

So, if a manufacturer bundles more than two products together, advertising a full package, but a few of the items do not correspond with the eventual objective, we will not recommend it.

Extensive Trial

A gym trainer taking notes down on a clipboard while someone is working out

Many companies claim that their products are backed by scientific evidence, yet some do not.

We want to make sure that the items you buy, especially the stacks, are backed up by clinical evidence.

It is not guaranteed that each product will function the same for everyone, but it can help with performance if used appropriately.

We triple-checked all of the products on the list and tested them for several months to see the most objective results.

Now, we can confirm that these companies offer facts to back up their claims.

Individual Needs

We want to ensure that the stacks offered here are correctly tailored to meet their promises.

It is not worth your effort to purchase something that will not help you attain your goal over time.

As a result, before investing in an expensive stack, ensure that our recommendations meet your requirements.

Also, keep in mind that a stack is not a magical pill. It requires action and commitment to reach your fitness objectives for it to work.

What to Consider Before Buying Pre-workout Supplement Stacks?

A gym coach writing down on a clipboard

Now that you know how we singled out the best products, here is what you should bear in mind when deciding on the best one for your needs.

Manage Your Expectations

While all of the stacks listed here have scientific backing, you should conduct your own analysis and properly study the nutritional values before making your final choice or purchase.

And keep in mind that not all promises made by a product will be valid for every person.

Our systems digest pre-workout supplements differently, so our responses to specific supplements might vary regardless of the facts.

Manage Your Expenditure

Buying a single product at a time may be fine if you only use one supplement to lose fat.

However, individually purchasing multiple products over the same period might rapidly become expensive. You can probably obtain the same supplements at a lower price when you purchase them in stacks.

In addition, you can save money on shipping because everything will be delivered together. After all, you're buying one overall product for losing weight.

Who Should Take a Weight Reduction Stack?

A doctor talking to a gym goer

You should take a weight reduction stack if you want to suppress your appetite, boost your energy and focus, and burn fat.

The best supplement stacks encourage your metabolic activities, thus causing your body to burn even more calories while building muscle mass.

Incorporating ingredients like caffeine and zinc will help you benefit from the thermogenic fat burner by boosting your strength and focus when exercising and lifting.

Who Shouldn’t Take a Weight Reduction Stack?

You should not take weight reduction stacks if you have harsh health issues or are sensitive to caffeine.

In addition, skinny and slender individuals should avoid taking these types of pre-workout fat-burning supplement stacks as their fat mass may be lower than recommended.

Other Resources You May Like:

FAQs

What is a Supplement Stack?

A supplement stack is a group of supplements that work together to provide better performance.

Do Weight Loss Stacks Work?

Yes, weight loss stacks work by incorporating ingredients such as caffeine and vitamin D that help you focus and feel energized during your workouts.

What Should I Stack With Whey Protein?

You should stack your whey protein with a pre-workout containing a fat burner, omega fatty acids, and essential amino acids (branched-chain amino acids).

Is It Safe to Stack Pre-workout?

Yes, it is safe to stack pre-workouts. It makes your supplements more effective, and you may get more pronounced results.

Which Fat Burning Stack Is Right for You?

After researching and testing numerous pre-workout stacks, Transparent Lab Fat Burning Essentials Stack stood out to be the most productive one.

This stack ensures you burn calories 24 hours a day, increases your metabolism rate and immunological function, and lowers cravings by suppressing your appetite and increasing the feeling of fullness.

Based on online evaluations, customer comments, and my personal observations, I believe this pre-workout stack has the best ingredients to assist you in reaching your fat-burning goals.

Our #1 Recommendation

Transparent Labs Fat Burning Essentials Stack

CTA of Transparent Labs Fat Burning Essentials Stack
Effectiveness
5.0
Ingredients
5.0
Price
4.9
Overall Score 5.0
5.0
Pros
  • Features science-backed non-proprietary blends
  • Recommended for those who are sensitive to stimulants/caffeine
  • There are no artificial sweeteners or coloring
  • Non-GMO and gluten-free
  • Get the BEST PRICE until the end of November
Cons
  • Not suitable for people sensitive to caffeine
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