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Omega XL Review
Does It Really Work?

Omega-XL Featured Image
Isaac Robertson
Written by Isaac Robertson
Last Updated on

Omega XL is popular for two main reasons -- the online raves and Larry King, of all people.

It claims to benefit those who suffer from joint pain and inflammation. As such, it’s a favorite supplement among older people, which probably explains Larry King’s strange, incongruous promotion of it… Although his face isn’t exactly the most inviting.

What is Omega XL?

Omega XL is a dietary supplement containing over 30 different fatty acids with a range of health benefits and joint pain relief effects. It contains Omega-3 fatty acids, EPA and DHA, all of which are sourced from natural ingredients.

Instead of obtaining these essential fatty acids from fish or algae, which can give a fishy aftertaste, this product sourced them from green-lipped mussels.

Arthritis organizations often recommend these natural ingredients to relieve pain in the joints, especially for older people who may be more sensitive to synthetic products.

According to the manufacturer, the main active ingredient in this product is a compound called PCSO-524 (sounds like a Star Wars droid) which is supposedly 89% more effective at reducing joint pain than standard fish oils.

The supplement is intended to be taken 1-2 times a day, depending on your weight. It is always advised to consult your doctor for a proper dosage recommendation, rather than relying solely on reviews.

​​Podcast host Joe Rogan includes this product ​as part of his supplement.

Omega XL Ingredients

Ingredients Banner

So, you’ve read the customer reviews, but what is actually in this product?

  • 1
    PCSO-524 – This ingredient’s full name is Perna Canaliculus Green lipped Mussel Extract, so I’m quite glad that they shortened it.
    Because this ingredient doesn’t come from fish, it doesn’t have a fishy aftertaste, which is something that a lot of users seem to like. According to a recent study, PCSO-524 is 89% more effective for joint pain relief when compared to regular EPA and DHA fish-based supplements, making it great for joint pain and inflammation.
  • 2
    Omega Fatty Acids – These fatty acids are known for helping to relieve painful joints, and some studies suggest that they also act as a natural anti-inflammatory, reducing inflammation.
  • 3
    Vitamin E – Vitamin E has numerous health benefits, such as improving skin and nail health. It’s a good addition to this patented oil.
  • 4
    Monounsaturated Olive Oil – Healthline claims that monounsaturated olive oil (i.e. extra virgin olive oil) is the healthiest fat on earth, and it’s easy to see why.

MUFAs (monounsaturated fatty acids) have been found to lower total cholesterol and low-density lipoprotein (LDL) cholesterol levels. In addition, some research shows that MUFAs may benefit insulin levels and blood sugar control, which can be helpful if you have or are at risk of type 2 diabetes.

Katherine ZeratskyDietitian

Omega XL Benefits

Omega XL contains ingredients that help with the treatment of joint pain and inflammation, making it popular with older people who might otherwise use regular fish-based oil to help their bones.

One of the nicest things about this product is that it comes in soft gel capsules, so you can wolf it down really easily. With its target market being on the older side, it makes sense to go with a soft capsule for this supplement. 

Many users, in their reviews, report improved mobility and reduced joint pain after taking the product, so it seems like it works for plenty of people out there.

It’s also a lot smaller than most fish oil capsules, which is another plus.


  • Extracted from non-animal sources
  • Toxin-free and fights free radicals
  • Improves joint health and can improve mobility
  • Small easy-to-swallow soft capsule

Omega XL Side Effects

Help In Joint Pain

So, what are the side effects of this potent medicine?

Well, there are side effects of having too many Omega-3 fatty acids (from any source), including high blood sugar, low blood pressure, and diarrhea.

When it comes to this product specifically, some users reported gaining weight after taking pills. However, it’s possible that they gained weight due to their diet and attributed it to the pills incorrectly. You know, you can’t trust everything you read on the internet.

Some users also said that it did little for them compared to their usual fish-based supplements.

Furthermore, the steep price is a common pain point among users, and there’s no denying that Omega XL is on the expensive side when compared to other supplements out there.


  • Quite expensive
  • Some customer reviews spoke about seeing no effects

How Much Does Omega XL Cost?

For a 60 capsule bottle, you can find the current most up-to-date price here.


FAQ Bnner

Is Omega XL better than fish oil?

This product may be better than fish oil for some users due to its active ingredients, which are sourced from mussels. Unlike fish oil, it contains Perna Canaliculus (PCSO-524), which clinical studies have found to be effective for treating joint pain and inflammation. For this reason, it is popular with people with joint health problems, according to reviews I saw.

Is Omega XL good for your heart?

This product is good for your heart due to the Omega-3 fatty acids that it contains. These fatty acids can help to decrease triglycerides, slightly reduce blood pressure, reduce the risk of blood clotting, and decrease stroke and heart failure risks. It can also help to reduce the risk of problems with an irregular heartbeat.

Does Omega XL help arthritis?

This product helps with arthritis and joint problems. This is due to its Omega-3 fatty acids and PCSO-524 – a unique active ingredient that clinical research suggests is 89% more effective at treating arthritis than regular fish oil. Nonetheless, some sufferers prefer using regular fish oil, so you should always see what works best for you personally.

Is Omega XL good for back pain?

This product is good for back pain in the sense that it reduces inflammation in your body, helping to reduce such pains.

However, supplements such as Omega XL are recommended to be consumed as part of a healthy diet and active lifestyle. If you’re looking to specifically target and reduce your back pain, you may want to look for other medicines.

Is Omega XL good for fibromyalgia?

This product could be good for fibromyalgia, as some studies suggest that Omega-3 fatty acids could help reduce symptoms of fibromyalgia if taken at the recommended dosage. However, if you’re suffering from fibromyalgia, you should consult your physician for the best medication, rather than looking solely at reviews.

Omega XL website

Is Omega XL good for lowering cholesterol?

This product can help to lower cholesterol due to its Omega-3 fatty acids content. This is because these fatty acids can effectively reduce bodily inflammation, decrease plaque growth in your arteries, and help to thin your blood. All of these effects combined can indeed reduce your cholesterol, especially if you eat a healthy diet too.

Is Omega XL good for diabetes?

This product can be good for diabetes if taken as part of a recommended healthy diet. For example, researchers found that Omega-3 fatty acids (DHA) can help to prevent fatty liver disease. The ingredients in it can also help to reduce the risk of type 2 diabetes, but you should always consult your physician about the best medication to take.

Is Omega XL a fat thinner?

No, this is not a fat thinner. Some users report side effects of loose stools and diarrhea, which can lead some people to think that the product is a fat thinner. However, it is primarily formulated for inflammation and joint pain relief in older people.

Is Omega XL approved by the FDA?

No, this product is not approved by the FDA. Many users still find the product to be useful, but the official US Food and Drug Administration has not yet given the product their seal of approval.

Omega XL: Does It Really Work?

Omega XL works for people with joint problems who need pain relief for better health. The content of each capsule can be very helpful if you’re finding that fish-based oil just doesn’t quite do what you need.

Furthermore, it has the added benefit of having no fishy aftertaste and no massive capsules, which is good for older people (or just people in general) who want easy-to-swallow supplements.

We highly recommend these supplements for improved joint integrity as you get older. With a cornucopia of Omega-3 fatty acids packed into each little capsule, it’s easy to see why this product has become such a phenomenon.

To know more about this product, head on to their website or contact their customer service support team anytime between 9am to 6pm EST.

About the author

Isaac Robertson

Isaac Robertson

I’m a personal fitness trainer and nutritionist living in sunny Indianapolis, IN. I’ve spent the last 8 years staying at the forefront of the health and fitness industry. In that time, I’ve helped hundreds of people shed the excess weight and get into shape, maintaining their healthy new lifestyle through proper training and eating habits. You can read more about me here​.