Omega XL Review (2024 Report): A Personal Experience

James Cunningham, BSc, CPT
Published by James Cunningham, BSc, CPT | Staff Writer & Senior Coach
Last updated: June 19, 2024
We personally test every product featured in our reviews and guides. By ordering products anonymously and getting a group of independent testers, we are able to get first-hand experience and provide data-driven recommendations. Learn more.

Omega XL is a popular supplement for two main reasons: online raves and Larry King. The product claims to aid joint muscle soreness, whether from aging or exercise.

Being a fitness enthusiast with a keen eye for supplements, I teamed up with our resident dietitian and spent almost a month's worth of research to test this product.

With mixed reviews and scientific scrutiny, how effective is Omega XL in addressing joint pain and inflammation?

Before trying it out, keep reading and find out if it's the right product for you.

What Is Omega XL?

Omega XL is a dietary supplement that contains a blend of more than 30 different omega-3 fatty acids. Instead of obtaining the essential fatty acids from fish or algae, this product sourced them from green-lipped mussels [1].

Many arthritis organizations have recommended natural ingredients (derived from the New Zealand green-lipped mussels) for joint pain relief, especially for older people who may be more sensitive to synthetic products than young people.

Based on what users who've taken the product told me, this joint supplement is intended to be taken 1—2 times a day, depending on your weight.

It is always advised to consult your doctor for a proper Omega XL dosage recommendation, rather than relying solely on reviews or manufacturers' claims.

Celebrities who use this supplement:

Suitable For Men & Women

Omega XL

Rated With Total Shape's Scoring System


Omega XL Active Ingredients: Are They Safe?

So, what does Great Healthworks claim to actually be in this product? How does it differ from standard fish oil?

Here's a list of ingredients that go into this supplement:

  1. PCSO-524™: According to a recent study from MDPI, Perna Canaliculus New Zealand green-lipped mussel extract, PCSO-524™, is 89% more effective for reducing joint pain than regular fish-based supplements [2]. This ingredient is unique to this supplement, but current studies fail to support the effectiveness of green-lipped mussel oil extract.
  1. Omega-3 fatty acids: Free fatty acids are known for helping relieve painful joints, and an article from NIH suggests that they also act as a natural anti-inflammatory [3]. However, its dose in Omega XL is relatively low compared to other omega-3 supplements.
  2. Vitamin E: Commonly found in olive oil, vitamin E has numerous potential benefits, such as improving skin and nail health [4].
  3. Monounsaturated olive oil: Monounsaturated olive oil (i.e., extra virgin olive oil) is known as the healthiest fat source on earth, and it’s easy to see why [5].

MUFAs (monounsaturated fatty acids) have been found to lower total cholesterol and low-density lipoprotein (LDL) cholesterol levels. In addition, some clinical research shows that MUFAs may potentially benefit insulin levels and blood sugar control, which can be helpful if you have or are at risk of type 2 diabetes.

- Katherine Zeratsky, Dietitian

Benefits: What Can You Expect?

Woman stretching outdoors

Based on my observation, the supplement is popular with older people suffering from osteoarthritis-related joint pain who might otherwise use standard fish oil extract.

However, most users report that Omega XL didn’t work to relieve their joint pain and inflammation due to arthritis even after months of use.

The manufacturer claims that the supplement may relieve muscle soreness due to exercise with an all-natural formula of fish oil and other ingredients. The nature of these ingredients helps elders avoid kidney or liver issues common with supplements that mainly use artificial ones.

However, I did not feel any significant relief in terms of delayed onset muscle soreness (DOMS) after workouts when using this product.

It comes in soft gel fish oil capsules, which is something most elders appreciate. My clients and I loved how it lacked the fishy aftertaste, unlike most omega-3 fatty acids supplements for joint health.

  • Extracted from green-lipped mussels to avoid a fishy aftertaste
  • Toxin-free and fights free radicals
  • Improves joint health and can improve mobility and vitality
  • Small, soft capsules
  • Quite expensive
  • Some customer reviews spoke about seeing no effects
  • It uses a proprietary blend
  • Quality of ingredients such as vitamin E, olive oil, and green-lipped mussel extract is not established

Omega XL Side Effects: Should You Be Worried?

There are side effects of taking too much omega-3 fatty acids (from any source), including high blood sugar, low blood pressure, and diarrhea [6].

After taking Omega XL dietary supplements, some users noticed gaining more weight. Our findings show that the other side effects were headaches and abdominal pain.

It's best to ask your healthcare provider before taking Omega XL or any supplement.

Some clients also mentioned that Omega XL did nothing to improve the mobility of clinical joint health symptoms.

However, the effect on joint pain relief seems to be a standard answer in several reviews -- joint pain symptoms were reportedly reduced, albeit temporarily.

Some users also noted that six Omega XL capsules a day or two capsules thrice a day is a good starting point as you gradually increase the dose to eight capsules to feel the desired results, such as improved joint health and joint pain relief.

Furthermore, the steep price is a common pain point among users, and there’s no denying that the Omega XL supplement is on the expensive side compared to other supplements out there.

Where Can You Buy Omega XL?

You can buy a bottle of Omega XL (either the 60-capsule or 300-capsule) on It is also available on the manufacturer's official website.

If you see Omega XL being sold on other platforms, be skeptical.

Based on my experience with ordering supplements in the past, you might get an expired or fake product from unofficial distributor websites.

Suitable For Men & Women

Omega XL

Rated With Total Shape's Scoring System


Omega XL Cost: Too Pricey?

Each Omega XL bottle has 60 capsules, which are good for 15 days only based on the recommended daily dosage of four capsules for joint pain. It costs around $50, depending on where you buy it, but you can also get two bottles for a discounted price of $94.99.

For active users of Omega XL, you can also buy the 300-capsule bottle at $219.99 to save more. But even with this discount, I still find it very expensive than other omega-3 supplements.

You can check this website for the most up-to-date price of this product.

We're currently working on a special coupon code for our readers, so check back here often.

Omega XL: Shipping and Returns

You can order your Omega XL bottles on, and it offers worldwide shipping at a fee.

For customers located in the US and Canada ordering on the manufacturer's website offers a 60-day money-back guarantee for any reason you're unsatisfied with the joint pain relief. Return the product (whether used or unused) within 30 days from the refund request.

Joint Supplement Alternatives

Countless products promise to relieve joint pain; we picked three to compare with Omega XL.

Relief Factor

Relief Factor is a good choice for joint pain relief, with a solid combination of all-natural ingredients like omega-3 fatty acids, resveratrol, turmeric, and icariin.

Notably, it features pure turmeric Curcuminoids and fish oil that can help reduce soreness and swelling, making Relief Factor an excellent option for those looking for a drug-free anti-inflammatory alternative.

Some users report the dosage is a bit high, with two gelcaps and two capsules twice a day.

Physio Flex Pro

What makes Physio Flex Pro stand out is its interesting omission of Omega-3. It does have, however, an adequate amount of glucosamine, a natural substance in cartilage and something you want to bolster for strong, pain-free joints.

Glucosamine is sourced from shellfish, making it advisable for people with shellfish allergies to speak with their healthcare provider before taking Physio Flex Pro.

Physio Flex Pro provides a transparent ingredient label where Omega XL amounts hide behind a proprietary blend.

A few Total Shape colleagues jumped on board to give Physio Flex Pro a try, and those with mild joint pain noticed a difference within a month. Others who suffer from more severe joint pain and stiffness reported more inconsistent results.

Osteo Bi-Flex

When talking to colleagues here at Total Shape, I learned that several of them have tried Osteo Bi-flex, perhaps one of the more well-known joint pain relief supplements on the market.

Two capsules daily give you a hefty 1500 mg dose of glucosamine to help alleviate minor joint discomfort and stiffness. Additionally, the formula includes boswellia, another known effective anti-inflammatory.

There is a mixed bag of reviews from people who use Osteo Bi-Flex, ranging from those who think it works excellently to those who experience some unpleasant side effects.


Is Omega XL Better Than Fish Oil?

Omega XL is better than fish oil for some users due to the green lipped mussel oil extract, PCSO-524™. But, clinical studies have declared it an effective ingredient for alleviating joint pain and muscle pain, same as fish oil.

Is Omega XL Good for Your Heart?

The Omega XL proprietary blend is good for your heart health due to its omega 3 fatty acids content. These can help decrease triglycerides, lower blood pressure, and reduce the risk of stroke and heart failure. However, it is worth noting that the body cannot absorb and use omega-3 fatty acids without other omega fatty acids.

Does It Help With Arthritis?

Omega XL may help with rheumatoid arthritis and other joint pain and problems due to its omega-3 fatty acids and PCSO-524™.

Is Omega XL Good for Back Pain?

Omega XL may be suitable for back pain as it claims to reduce inflammation in your body. However, if you’re looking to target and reduce your backache specifically, you may want to look for other joint health supplements.

Is Omega XL Good for Lowering Cholesterol?

Omega XL is good for lowering cholesterol due to the omega-3 essential fatty acids from New Zealand green-lipped mussel extract. It can effectively reduce body inflammation, decrease plaque growth in your arteries, and help thin your blood while alleviating joint pain.

Is Omega XL Good for Diabetes?

Omega XL may be good for diabetes if taken as part of a recommended healthy diet. According to studies, omega-3, together with omega-7 and -9, can help prevent health issues such as fatty liver. However, you should always consult your physician about the best medication and supplement to take.

Is Omega XL a Fat Thinner?

No, Omega XL is not a fat thinner. Some users share side effects of loose stools and diarrhea, which can lead some people to think that the product is a fat thinner. However, it is primarily intended to relieve or reduce joint pain in older people.

Is Omega XL Approved by the FDA?

No, Omega XL supplement is not approved by the FDA.

Our Verdict ony Omega XL

Omega XL is beneficial for older people with joint issues and athletes managing muscle soreness, but we recommend speaking to your medical professional before taking it.

It's akin to other omega-3 supplements but stands out with its non-fishy taste due to green-lipped mussel-derived omega-3s. However, the efficacy and vitamin E quality are debated based on several user comments.

If you’re looking for a premium omega-3 supplement, OmegaWell from Live Conscious is an excellent alternative, featuring high EPA (800 mg) and DHA (600 mg) content, no preservatives, and a commitment to 100% sustainable ingredient sourcing.

We Recommend This Instead

OmegaWell by Live Conscious

Rated With Total Shape's Scoring System

  • The added lemon flavor reduces the chance of fishy burps (from the fish oil)
  • One of the strongest doses of EPA and DHA
  • Available with good bulk-order discounts
  • The small soft gels seem to be easy to swallow
  • Get the BEST PRICE until the end of June
  • A bit pricey
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About The Author

James Cunningham, BSc, CPT
Staff Writer & Senior Coach
James Cunningham, BSc, CPT holds a BSc degree in Sport & Exercise Science from University of Hertfordshire. He's a Health & Performance Coach from London that brings a unique blend of academic knowledge of health supplements and practical exercise experience to the table for his readers.
Learn more about our editorial policy
Dr. Harshi Dhingra, MBBS, MD is a published peer-reviewed author and renowned physician from India with over a decade of experience. With her MBBS from Bharati Vidyapeeth and an MD from Rajiv Gandhi University, she actively ensures the accuracy of online dietary supplement and medical information by reviewing and fact-checking health publications.
Learn more about our editorial policy
Dr. Kristy June Dayanan, BS, MD is an author with a BS degree from University of the Philippines and an MD from University of Perpetual Help System. Her ability to simplify medical science complexities and dietary supplement jargon for the average reader makes her a valued medical fact checker and reviewer.
Learn more about our editorial policy

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9 thoughts on “Omega XL Review
Does It Really Work?

  1. I have arthritis in my back, legs, and headaches from migraines, and I would say that it definitely targets the inflammation.

  2. how come it doesn’t say how much will be taken out of your account ?

  3. call your bank and they will stop it but may charge depending on bank you use

  4. It works GREAT FOR ME, MY WIFE AND MOTHER WHO IS 76 years old , I’m aware that some people have symptoms that this won’t help and ARE THE FIRST TO COMPLAIN but after MY OWN PROVEN TEST STUDY against store bought products , my wife started using it AND AGAIN with GREAT RESULTS and now won’t go without it. We were introduced to Omega XL by my old mother who gave it to us for free to try. Now she gets it free from our subscription.,,

  5. It’s a good thing everything is listed what’s in Omega XL in this article.

  6. Thank you for all the posts on this product. Not spending any money for this omega xl fraud

  7. Good day! I simply would like to offer you a big thumbs up for your great information you’ve got right here on this post.
    I’ll be coming back to your website for more soon.

  8. Maintaining healthy joints is crucial for any fitness routine. Glad to hear Omega XL provides so many benefits. Will have to give it a try.

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Our ingredients score is based on 3 factors including: transparency, blend disclosure, and dosage accuracy. We conduct third-party lab verification of ingredients. The score is an objective measure of the lab test results compared to the product label. For more information see our ingredients score explanation here.
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