Phen375 vs PhenQ (2024 Review) Which One Should You Buy?

Lisa Lorraine Taylor, BSc, CPT
Published by Lisa Lorraine Taylor, BSc, CPT | Staff Writer
Last updated: June 20, 2024
We personally test every product featured in our reviews and guides. By ordering products anonymously and getting a group of independent testers, we are able to get first-hand experience and provide data-driven recommendations. Learn more.

I think this could have been one of the most heated debates we’ve had in the office. Every time we started discussing the merits of PhenQ vs Phen375, we rarely made unanimous agreements.

The only way we could find a common ground was to have a nutritional scientist take a closer look, and we put a testing team together to get some real life experience.

There were a few surprises in this PhenQ vs Phen375 research for us, and we thought we’d give you some insights.

What Is Phen375?

Phen375 on top of a kitchen table

Phen375 is a weight loss supplement that claims to increase your metabolism rate and reduce hunger cravings at the same time.

The company has based the formula on a few carefully selected scientifically proven ingredients to help burn fat.

This is also one of the few weight loss supplements that seem to be specifically marketed for women.

It means no more worrying about improper dosages and other side effects. As such, a lot of our female clients have been using it with some success.

Our test results also showed that Phen375 might work well as an energy booster, so that’s something worthy of consideration as well.


What Is PhenQ?

PhenQ bottle

PhenQ is an excellent fat-burning supplement that also claims to target the metabolic processes that result in excess fat being stored as fat.

PhenQ weight loss pills are based on a few carefully chosen ingredients, and we found some surprising research to back up the formula.

We also saw got positive PhenQ review feedback from our testing team that mentioned it improved physical and mental energy levels.

I have been using both products for a few months, but before we get to our results, let’s show you the ingredients.

Our Rating



Rated With Total Shape's Scoring System



Our Testing Approach

A diverse group of my clients, both male and female, eagerly stepped forward to evaluate the two prominent fat burners, Phen375 and PhenQ.

To ensure a comprehensive and unbiased assessment, we carefully selected participants, considering the unique metabolic differences between genders.

We organized them into two balanced teams, each delving into one of the products for a month-long trial.

Prior to the experiment, I meticulously assessed their existing dietary habits, fitness regimens, body fat ratios, and ongoing weight loss trajectories to set a clear benchmark.

While both teams witnessed commendable fat reduction, as evidenced by their physical metrics, one fat burner subtly outshone the other in efficacy.

Common Ingredients

The first thing I should mention is that there is no easy way to lose weight.

Neither PhenQ nor Phen375 diet pills contain ingredients that would allow you to sit on the couch all day while you work your way through a box of donuts. Remember, there is no magic diet pill. You have to put in the work to ensure your long-term weight-loss success.

But fat-burning supplements may support the work you put in at the gym and in your diet plan.

Let’s see how these two products claim to do that.

1. L-Carnitine

L-Carnitine ingredient

L-carnitine is an amino acid that researchers from The Swedish School of Sport and Health Sciences have shown to play a role in releasing stored fat and transforming it into energy, improving work output by 11% [1].

You sometimes see this ingredient in pre-workout supplements, but it seems like the weight loss industry is paying more attention to it now.

2. Caffeine Anhydrous

Many people find this surprising, but caffeine may trigger thermogenic processes that help to burn fat [2].

This happens by slightly raising your core body temperature and burning off some body fats in the process.

In my experience with a few different fat-loss supplements, I have found these two ingredients to be among the most important.

3. Cayenne Pepper

Cayenne and black pepper extracts are what give the peppers their spicy taste.

They also have a similar effect as caffeine, and by combining the two, you may be able to increase how long thermogenesis would last. And from my experience, I can say that you don't get a spicy aftertaste with these supplements.

Unique Ingredients

This is where things might get a bit more interesting.

My dietitian gave me some interesting observations that showed that there are a few reasons to favor one of these products.


Coleus Forskohlii leaves

1. Coleus Forskohlii Root

We’ve noticed this more often in recent years, and the Phen375 weight loss pill claims to use it because it may have a positive effect on energy levels.

However, some research we found indicates that there isn’t much evidence after going through some extensive trials [3].

It’s just something that didn't quite convince us.

2. Citrus Aurantium

This was a new ingredient for us, but we did find some interesting clinical trials on this. One, in particular, found that regular supplementation may help to release stored body fat just a bit faster [4], which might have a positive impact on your body shape.

3. Dendrobium Nobile Extract

This is apparently extracted from orchids, and there is some evidence that it may work as an appetite suppressant. We did find a few Phen 375 reviews that mentioned a positive impact during extended fasting periods.


1. Chromium Picolinate

This seems to be a surprisingly great ingredient that really should be included in every weight loss supplement. Studies have shown that it may have a significant impact on satiety and regulation of blood sugar levels [5].

It has helped me to avoid going for those snacks in between meals, making it easier for me to avoid unhelpful calories.

“Chromium is a mineral that enhances insulin, a hormone that's important for turning food into energy. Your body also needs it to store carbohydrates, fats, and proteins. So there are claims that chromium supplements can lower your appetite, help you burn more calories, cut your body fat, and boost your muscle mass.”

2. Nopal

Similarly, this cactus extract may be full of fiber that would swell up in your stomach. The result is that you should feel full for longer, which should help you stick to your diet a bit more easily.

And it’s these two unique PhenQ ingredients that we think make it the more popular choice with people looking for a broader range of benefits with fewer side effects.

Where To Order

hand view of a person typing on a laptop

It's best to order PhenQ or Phen375 diet pills from the official website. There have been too many reports in recent years about counterfeit supplements, and it’s also the only place you’ll get the money-back guarantee.

So, stick with the official website to avoid running into problems. Any time I have placed an order, it arrived within 3-4 days, which is a great service.

Customer Reviews

We wanted to make sure you also got some feedback from other customers, so we picked a few for each product.

"He used PhenQ for his weight loss journey, and by exercising four days a week was able to lose 30 pounds in six months."
- Johnny from London

"Susan is a long term user of Phen375 and likes that it’s not too strong due to a more female supportive formula."
- Susan from Miami

"Jenny also had success with PhenQ, which she believes helped her extend intermittent fasting periods."
- Jenny from Sacramento

"Juan used Phen375 but didn’t find it made him feel full for long enough, which resulted in some snacking."
- Juan from NY

PhenQ vs Phentermine

In my personal journey to achieve a consistent weight, I've come across various weight loss supplements, and along with PhenQ, the name Phentermine came up pretty often.

While PhenQ is a natural supplement and boasts many benefits, from appetite suppression to energy boosting, Phentermine is a prescription medication and is known for its appetite-suppressing properties [6].

I'd always opt for PhenQ due to its gentler approach and minimal side effects, and I wouldn't recommend trying Phentermine because it's a prescription medication known for its potential side effects.


How Long Will It Take for PhenQ To Work?

It may take three to four months to see some results with PhenQ. Unlike other supplements that promise fast results, PhenQ requires time to work on your torso.

Is PhenQ Worth It?

Yes, PhenQ is worth it. As long as you follow a calorie-restricted diet, PhenQ effectively reduces weight and avoids weight gain without exercise.

Our Verdict on PhenQ vs Phen375

Between PhenQ and Phen375 weight loss pills, I think that our scientific research and testing support PhenQ just a bit more.

This also seems to be backed up by my own experience, where I found that it tended to make me feel full for longer without any noticeable side effects.

Order yours today from the official website, and if you don’t like it, you’ll get a money-back guarantee.

Our #1 Recommendation



Rated With Total Shape's Scoring System

  • Vegetarian and vegan friendly, catering to diverse dietary preferences
  • Chromium Picolinate aids in metabolism and fat storage
  • B Vitamins support energy and mood, beneficial for weight management
  • Suitable for a wide range of users with different weight loss goals
  • Get the BEST PRICE until the end of July
  • Potential side effects like headaches and restlessness in some users
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About The Author

Lisa Lorraine Taylor, BSc, CPT
Staff Writer
Lisa Lorraine Taylor, BSc, CPT holds a BSc degree in Holistic Nutrition from Clayton College of Natural Health and is the owner of Taylor Made Fitness. Her philosophy centers on cutting through the hype and misinformation surrounding dietary supplements, focusing instead on practical, science-backed strategies for health and weight loss.
Learn more about our editorial policy
Dr. Harshi Dhingra, MBBS, MD is a published peer-reviewed author and renowned physician from India with over a decade of experience. With her MBBS from Bharati Vidyapeeth and an MD from Rajiv Gandhi University, she actively ensures the accuracy of online dietary supplement and medical information by reviewing and fact-checking health publications.
Learn more about our editorial policy
Dr. Kristy June Dayanan, BS, MD is an author with a BS degree from University of the Philippines and an MD from University of Perpetual Help System. Her ability to simplify medical science complexities and dietary supplement jargon for the average reader makes her a valued medical fact checker and reviewer.
Learn more about our editorial policy

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