Connor Sellers
Published by Connor Sellers
Fact checked by Donald Christman, BHSc FACT CHECKED

I think this could have been one of the most heated debates we’ve had in the office. Every time we started discussing the merits of PhenQ vs Phen375, we rarely made unanimous agreements.

The only way we could find a common ground was to have a nutritional scientist take a closer look.

There were a few surprises in this PhenQ vs Phen375 research for us, and we thought we’d give you some insights.

What Is Phen375?


Phen375 is a weight loss supplement that claims to increase your metabolism rate and reduce hunger cravings at the same time.

The company has based the formula on a few carefully selected ingredients that are scientifically proven to help burn fat. More on that shortly.

This is also one of the few weight loss supplements that seem to be specifically marketed for women. And a lot of our female clients have been using it with some success.


We also saw some comments online stating that Phen375 might work well as an energy booster, so that’s something worthy of consideration as well.


What Is PhenQ?


PhenQ is a fat burning supplement that also claims to target the metabolic processes that result in excess fat being stored as fat.

This is a great idea that many people have claimed could better help with long term weight management.

PhenQ weight loss pills are based on a few carefully chosen ingredients, and we found some surprising research to back up the formula.


We also saw quite a few positive PhenQ review comments that mentioned it improved physical and mental energy levels.

We have been using both products in our team for a few months, but before we get to our results, let’s show you the ingredients.


Common Ingredients

The first thing I should mention is that there is no easy way to lose weight.

Neither PhenQ or Phen375 diet pills contain ingredients that would allow you to sit on the couch all day while you work your way through a box of donuts. Remember, there is no magic diet pill.

But fat burner supplements may support the work you put in at the gym and in your diet plan.

Let’s see how these two products claim to do that.

1 - L-Carnitine

Acetyl L-Carnitine (1,500mg)

L-carnitine is an amino acid that researchers have shown to play a role in releasing stored fat and transforming it into energy [1].

You sometimes see this ingredient in pre-workout supplements, but it seems like the weight loss industry is paying more attention to it now.

2 - Caffeine Anhydrous

Caffeine Anhydrous

Many people find this surprising, but caffeine may trigger thermogenic processes that help to burn fat [2].

This happens by slightly raising your core body temperature and burning off some body fats in the process.

3 - Cayenne Pepper

Cayenne Pepper Extract

Cayenne and black pepper extracts are what give the peppers their spicy taste.

They also have a similar effect as caffeine, and by combining the two, you may be able to increase how long thermogenesis would last for.

Unique Ingredients

This is where things might get a bit more interesting.

Our dietitian gave us some interesting observations that showed that there are a few reasons to favor one of these products.


Coleus Forskohlii

1 - Coleus Forskohlii Root

We’ve noticed this more often in recent years, and the Phen375 weight loss pill claims to use it because it may have a positive effect on energy levels.

However, some research we found indicates that there isn’t much evidence after going through some extensive trials [3].

It’s just something that didn't quite convince us.

2 - Citrus Aurantium

This was a new ingredient for us, but we did find some interesting clinical trials on this. One, in particular, found that regular supplementation may help to release stored body fat just a bit faster [4], which might have a positive impact on your body shape.

3 - Dendrobium Nobile Extract

This is apparently extracted from orchids, and there is some evidence that it may work as an appetite suppressant. We did find a few Phen 375 reviews that mentioned a positive impact during extended fasting periods.


1 - Chromium Picolinate

This seems to be a surprisingly great ingredient that really should be included in every weight loss supplement. Studies have shown that it may have a significant impact on satiety and regulation of blood sugar levels [5].

That should help you to avoid going for those snacks in between meals.

“Chromium is a mineral that enhances insulin, a hormone that's important for turning food into energy. Your body also needs it to store carbohydrates, fats, and proteins. So there are claims that chromium supplements can lower your appetite, help you burn more calories, cut your body fat, and boost your muscle mass.”



2 - Nopal

Similarly, this cactus extract may be full of fiber that would swell up in your stomach. The result is that you should feel full for longer, which should help you stick to your diet that bit more easily.

And it’s these two unique PhenQ ingredients that we think make it the more popular choice with people looking for a broader range of benefits with fewer side effects.

Where To Order

where to order

We’ll get to our final recommendation shortly, but if you’re planning to buy either PhenQ or Phen375 diet pills, then I would strongly suggest that you only buy them from the official website.

There have been too many reports in recent years about counterfeit supplements. In a best-case situation, they will do very little for your weight loss.

But you’d also be taking considerable risks with side effects that could result in health issues.

So, stick with the official website to avoid running into problems.

It’s also the only place you’ll get the money-back guarantee.

Customer Reviews

We wanted to make sure you also got some feedback from other customers, so we picked a few for each product.

He used PhenQ for his weight loss journey, and by exercising four days a week was able to lose 30 pounds in six months.


- Johnny from London

Jenny also had success with PhenQ, which she believes helped her extend intermittent fasting periods.


- Jenny from Sacramento

Juan used Phen375 but didn’t find it made him feel full for long enough, which resulted in some snacking.


- Juan from NY

Susan is a long term user of Phen375 and likes that it’s not too strong due to a more female supportive formula.


- Susan from Miami

PhenQ vs Phen375: Which Should You Buy?

Between PhenQ and Phen375 weight loss pills, we think that scientific research supports PhenQ just a bit more.

This also seems to be backed up by our own experience, where we found that it tended to make us feel full for longer without any noticeable side effects.

Order yours today from the official website and if you don’t like, you’ll get a money-back guarantee. Also, make sure you let us know how PhenQ or Phen375 worked out for you



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About the author

  • I’ve tried your #1 and #3 recommendation and I liked PhenQ more because I lost more weight. These pills are definitely the best thermogenic fat burner for men (not sure for the ladies tho)

  • I immediately purchased one of the products highlighted by Isaac. Since then, I have been taking for a week now. I never usually take any of this kind of pills for anything, but I wanted to shed a few pounds that I have gained over this quarantine period which has been hard to get off and it is pissing me off. I’m taking two pills twice a day. I don’t know if it’s just me, but I do feel and notice an immediate boost in energy and a little parched. So, make sure you stay hydrated with this when taking this. Also I ride my bike at least 3 times a week and it would take me about 45 min in before I start sweating before I started using this. Now with the pills, I am totally drenched in sweat 15 min into my activity. So evidently something extra must have been working on with me. I don’t know if this is the pill or not, but I find myself eating less and not snacking as much. I can’t even finish 1 plate of food anymore. My body does feel like it is changing, and I can already see a little difference from now even after just a couple of weeks. I will keep taking and hope for the best. Overall, I am glad I listened to Isaac about his thoughts. Please do listen to him as well.

  • Before I will start, I would like to extend my gratitude for the effort Isaac has been putting to help us with our decisions. Thank you, man. Now, let me tell you what I have experienced. Actually, this product is pretty amazing!!! A big disclaimer is if you put in the work. As I have noticed, it decreases my appetite so I’ve found that I only eat about half portions at meal times. I eat kind of healthy to begin with but I do not stick to a strict or specific diet as some of you may have been doing. I purchased this not a few while back and started using it immediately after preparing my needs. It gave me energy to do extensive physical activities, and even just do simple household tasks which we all men avoid to do. When I started, I initially weighed in around 160 pounds. I had previously been prescribed with another product by a friend but I was looking for something that fits my budget. I wanted to lose 10 more pounds and figured I could do so with a bottle of this. Just this morning, I weighed myself and I am 150.2. To be honest, I don’t work out every day since I am busy with work, but this has really controlled my appetite which has always been my biggest issue. So my advice is for people out there is listen to what Isaac say. He truly knows what he is sharing and people must try it! It’s at a great value to try it out because it really helped me deal with losing that last stubborn few pounds. Thankful for Isaac. Let’s keep on losing those unwanted pounds!

  • One of these product works and I’m glad I stumbled upon your post before actually purchasing one! But, it would be unfair for the product if it works and you are no doing your part. So you also have to do your part. What I am trying to say is this. I’m a huge snacker every afternoon. So at noontime I take 2 pills. It holds me over til dinner. Simple as that! I’m up before the sun rises every day. I have would take the usual breakfast. Before lunchtime, I have to eat a nice size lunch. Then by noontime, I pop 2 of these pills and these pills will take me until the sun sets. When the night comes, I eat dinner. Done and that’s my usual routine. What may have worked for me may not necessarily work for you. So you have to figure out for yourselves the right time to take these pills and you’ll see results! Thanks Sir Robertson. I am a huge fan of yours.

  • At first I was unsure about this product but when I started doing my research, I ended up in Isaac’s post. I have been trusting him for my decisions when it comes to this thing. I got encouraged to order some right away and believe it or not, that was the last money I had left on my debit card. But I wanted to try this product so much that I said why not plus the words came from your trusted writer Isaac who had a lot to do with me making up my mind whether I was going to try this product or not. When I finally ordered it, I couldn’t wait to get it. When I received it, I started using it immediately and I started seeing results immediately. I am a part of a gym so I’m working out as well. the stubborn pounds are just melting off like sweat. It’s like someone put it in a pot and it just melted away like magic. I am glad I listened. Thanks Isaac.

  • I’ve just started using this product when I found out that Sir Isaac has done and posted his thoughts on these. As soon as I began, I have noticed a significant reduction in my appetite. I’m usually someone who has constant cravings that are uncontrollable – not just simple hunger, but that pregnancy-strength cravings similar to what my wife has experienced when she was pregnant. Those cravings that can only be satisfied with whichever specific food. With this product, I’ve found that I’m much more in control of what I actually put in my mouth, not just how much, and it’s really helped me stick to my goals. I also have really appreciated the professionalism of Isaac in the way he conveys his thoughts. It’s clear that he genuinely cares about his avid readers’ experience. 10/10 will purchase again when I am out of stock. Thanks!

  • I have always been skeptical of these kinds of products. I have researched so much throughout the years on many brands and products. I finally decided to give this brand and formula a shot since Isaac has been my trusted writer over the years. When I tried it, actually it works. I started out with one pill as recommended for about a week, then been doing 2 since then. I’ve lost about 10 pounds, and I’m still using the product now as of writing. I would recommend these if you’re looking for a true pill that works like magic. I wasn’t sure if it would work, but it does, and I’m glad I bought them. Thanks for encouraging me Isaac. I am a more invested reader starting now.

  • First of all, thank you Isaac for the thorough list. I tried this because the I have been his reader since who knows when. Also I’m the father of the bride in 3 weeks with a hundred things to prepare for and lots of pictures to pose for soon. This product is amazing. I’m only on day 2 and will keep you guys posted in a month if I remember to write it. Day 1 was unreal. I had no idea I could feel so alert, able to make quicker decisions that have been hard planning a wedding. My house hasn’t been this clean in a while and I had energy all day to clean it. My mood was better than it’s been in a long time. While I’m certainly not an expert in this area, I’m so glad to feel the benefits of this on day 1 taking one pill twice a day. I can feel the appetite suppressant working however I’m more happy about the mood boost and energy at this time. If your hesitant to try a product like this, I can say this is worth a try for everything it says! Plus Isaac has written it out so there is nothing to worry really. I’m looking forward to seeing more results after a month on this product.

  • I have seen several negative posts about these products however I did not believe them knowing that Isaac is my most trusted writer when it comes to this topic. After buying it, I immediately took it up. It works fine to me and lost 15 pounds already in a month. Of course, you also have to do your part. Try not to eat anything that’s white like bread, rice, and flour. Also drink greens such as blend, shake or smoothies whichever works for you. For dinner, I eat salad. Most important is that you eat right. If you are full then don’t eat until your tummy tells you to eat something. Take a pill when you wake up, drink greens for lunch then have healthy meal for dinner. You cannot just take a pill and not doing anything or eat all you want to. This WILL NOT help you lose weight!!!

  • I don’t normally use products or dietary pills but when weight keeps you from doing what you want you’ll find any means to change that. Initially, I started using this product to help my metabolism in conjunction with going to the gym and only a few weeks after I started I’ve already lost 8 pounds. If this product didn’t work for me then I wouldn’t leave a comment like this. But it does. So if you’re considering a product that will help you shed off those pounds, this is what I would consider a tried and true product you should consider purchasing. Thank you Isaac. I am new to your blog but I am glad I listened to your loyal readers.